Microbiology and Immunology

Hi, I am computer scientist with a strong background on mathematics and logic. In Maths we have fundamental books like the "Principia Mathematica" from Russel, Whitehead which more or less acts as the foundation of modern mathematics. I am looking for such books for medicine, which a non-medicine can read and comprehend from the ground up. My first interest is the creation process of a disease caused by microbes and virus. As far as I know the Microbiology began with Pasteur and his postulates about microbes. What books can you recommend? P.S.: My native language is german, so books in german are also welcome.

Dear "Biology Experts" and everyone else. How're y'all doin'? Been away ... I was in the hole for while for ... uh .. offensive behavior. But all that aside ... here's an easy, topical query I'm sure many of you "Experts" can answer with certainty ... Where is info, if any, on animal (non-human) pandemics (or epidemics)? Don't bring up bat white nose syndrome, but you may bring up bees (https://en.wikipedia.org/wiki/Colony_collapse_disorder). Hell, you can even bring in plant pandemics (blights, etc, https://en.wikipedia.org/wiki/Blight). But large mammals -- and esp. primates -- is the cash cow here, folks.

🧬 anti malarial drug hydroxy chloroquine phosphate is useful or not and the RNA is replication process ending destroy the varian in the human plasma lungs is always affected with CoVD 19 but inhalation formulations more effective on the lungs

What are the immunity mechanisms in relation to the protection against lung cancer? What is the difference in energy obtention between normal cells and cancerous cells? How does the body protect itself against a cancerous cell or formation? How does stress affect the cells, and how can it be linked to causing cancer? How can we change so that environmental factors in lung cancer can decrease? How can biomimicry help us in the fight to cure lung cancer?

Not sure whether this is better for here or Biology, but I'll put it here for now. I assume most of you have already heard of China's coronavirus outbreak, but in case you haven't, a little refresher... https://www.businessinsider.com/wuhan-coronavirus-chinese-wet-market-photos-2020-1 A. So does this suggest doing farming within the city limits of a major city is more likely to spread disease than relegating the farming tasks to small towns? Does it depend on whether it's meat farming or just vegetable farming? Either way, how come China often does their farming in major cities, while in the United States, farming's considered a "small town" thing?…

I'm in the process to achieved a reasoning about a way to slow down a Coronavirus, type Delta, infection by another one of lesser importance. Could you please giving me some argue about those two sheets: WORKING AROUND T-CELLS CYTOTOXIN The point is that Coronavirus is not possessing the good membrane proteins, or viral peptides, to be the target of the immune system correctly, because, if it was the case, vaccine will arise rapidly. So why not insert a regular virus that possess what is missing, like flu virus, that is killed almost easily by the body. That Virus shall be from a strain where one or many proteins are missing but included in the C…

Good afternoon! I have a question about an experiment. Which transfection reagent works best for a reporter gene assay with luciferase on stem cells? Thanks!

Hello all, what does the body do with ingested substances that are not supposed to be there, eg soap, chlorine from swimming pools, lipstick and face powder and all other such foreign stuff? Regards

So walmart is going to be cutting hours to reduce infection. Hear me out on this. What if instead of reducing hours they dont allow entry into the store and require all orders be done online for pickup. Give Walmart employees more hours. Only load groceries into vehicle trunks. People who travel their on foot have to join a queue outside. What's better here, reduced hours that could confine more people together in larger shopping densities, or people having less interaction with each other? https://www.google.com/amp/s/wgntv.com/news/coronavirus/walmart-to-cut-hours-to-combat-covid-19/amp/

Good morgning, I used a serum/plasma kit. After phase separation there should be 3 phases. Aqueous phase, white interphase and a red organic phase. In some of samples there did not create an aqueous phase after some time. Does anyone know the solution to this problem? Thanks in advance!

There is no animal serum against hiv even if bovines(for example) produce Hiv antibodies...

Hi all. I see the act of installing filters to improve drinking water a double edge sword. It may stop some microorganisms, minerals, debris, perhaps toxins from drinking. But right now and during all the time you are not serving a glass of filtered water, inside the filter there is a multitude of undesirables that were previously captured and held in, as intimate soup with the water for the next glass you will serve. Water that can be in a reasonably good condition being forced to pass trough the rotting filter accumulations. What are the alternatives ? What process to improve drinking water for better and more convincing methods that does not use fil…

I have a question and wasn't quite sure where I should post it, but I thought here, rightly or wrongly might be a good choice. I have been thinking about the differing response to COV-19 by age and pondering on why this occurs. The immune system in animals has two components, innate and adaptive, innate is the type we have at birth and adaptive is learned by exposure to infective agents such as a virus. Adaptive immunity is acquired throughout life by exposure to illness and vaccination, the adaptive immune system stores the knowledge in memory T-cells as it encounters a pathogen. As we age our ability to autophage T-cells and produce new o…

Has anyone considered the application of static electric, tesla electric on any virus dish or the effects of sound on reducing the virus cell membrane then trying the fore mentioned method of static according to nostradamus theory this will be a way of us dealing with the new viruses. Read his book

90% of Lupus patients are female. While estrogen itself seems to have no effect on the spread of Lupus, could the estrogen steroid hormone Estradiol be involved? It seems like it’s mostly involved with sexual processes: however, it also has important effects in the brain, skin, and liver. Estradiol is also produced in small amounts in males. Could a surplus or deficiency of Estradiol be linked to the spread/severity of Lupus?

I found this tracker which is updated daily that might be of interest to some. This is a screenshot for today. You can zoom and move the map. https://gisanddata.maps.arcgis.com/apps/opsdashboard/index.html#/bda7594740fd40299423467b48e9ecf6

As far as I understand, Cas9, being given a sample of target DNA, will find a virus which DNA has a matching sample and destroy it. Can this be used to cure all viral deceases for humans? If a virus' DNA is known, can it be loaded into Cas9 and made into an injection for example?

Following any kind of prostate surgery, nerves responsible for erection are commonly damaged. Sonic Hedgehog protein (what a name) can supposedly speed up the regeneration of these nerves, but it apparently has to be delivered through a nanofiber hydrogel. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5578182/ This is something which I've never heard of being commonly prescribed... would have no idea about how to apply to get this treatment.

I am collaborating with a microbiologist to test some compounds to see whether or not they possess antibacterial properties. These compounds are either neutral or bear a single negative charge near pH 7, and they have aromatic rings. The compounds we have tested so far are soluble in DMSO, but modestly soluble in ethanol (less than 10 mg/mL), and probably not soluble in unbuffered water. The assay begins with adding the compound to a disk that is placed in contact with bacteria. My question concerns solvents that would be appropriate to use to dissolve the compounds. I assume that one control is to try the solvent without the compound of interest. Are the…

SPI009's chemical name is 1-((2,4-Dichlorophenethyl)Amino)-3-Phenoxypropan-2-ol. What kind of treatment would use this (oral ingestion? intravenous therapy?), and how might someone get this on the market? Here is some literature https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5809444/

I can visualize what it looks like to take oral or intravenous antibiotics... but still don't know what using a dendrimer actually involves. Is it a substance added to an injection? I have no idea. Asking because there's literature about putting antibiotics in dendrimers as a way to cure drug-resistant infections. The question is what does using a dendrimer actually involve, AND how do patients even get access to dendrimers?

Hi, As the question says, I am wondering if eukaryotic (mammalian) cells such as endothelial cells (or whatever really) have intra-cellular defences against viral infection. I mean specifically if 1 cell infected with viral stuff (protein, RNA, DNA), can it neutralise this threat and continue to live and function afterwards. I am aware of TLR's being able to increase Interferon production, but that influences the viral response of the body as far as I understand, not the survival chance of the individual cell. Apoptosis is of course not what I mean, nor is the slowdown/shutdown of translation through kinases that recognise viral RNA/DNA. I suppose some…

Hi, I wonder why you are more prone to get sick (get colds) when you are cold. How does the immune system get weaker?

we have to face land pollution, food pollution, water pollution, and air pollution. The last one is unavoidable; it is equal to everyone. how do people who live in heavily polluted areas protect themselves? how does it affect their immune system ? Any chance people affected in long run grow any ability to fight it ? How does their immune system respond to it ? Is it possible their immune system could gradually gain the power against it ?

1. What effect does purposely stimulating the immune system by exposure to an allergen have on the production and release of T-Cells and what’s the effect of this increased activation of the immune system on internal pathogens in general and also specifically on toxoplasma cysts? 2. What’s the effect of pure isolated histidine consumption on histamine levels, the subsequent effect on the immune system and on the production and release of T-Cells? 3. Besides perfecting the diet and lifestyle such as correcting Vitamin A deficiencies, what are some ways to purposely induce an immune response and increase production and release of T-Cells f…