Organic Chemistry

Is the cost of producing biofuel (or really any alternative fuel in this argument) really that much greater than fracking/digging up fossil fuel? Correct me if I'm wrong but the big sink in in alternative fuels is the production of the fuel. You don't get more energy out of it then it costs to make it. So you're breaking even or making a little profit.Whereas with fossil fuels, the "assembly" of crude oil molecules has already been done for us by the plant and animal decomposition under heat & pressure for millions of years. All we have to do is frack/dig it up. Looking at the size and operation of oil rigs and fracking companies, you'd think it would cost much more …

I am trying to find the product and draw a 3D structure from putting together Fe(H2O)4Cl2 + 3 ( H2N - C-C-H2N) " ethylenediamine". Any help appreciated

Hello everyone! I was wondering if anyone could show me how the amide on the drug Ibrutinib would react with LiAlH4? I understand how amide would normally react with LiAlH4 but I am confused as to how I would react this amide because of the placement of the N. Any help would be greatly appreciated. Thank you I've attached an image of Ibrutinib so you can see the amide that I am trying to react !

Hello everyone! I was wondering if anyone could help me with a functional group formation and curly arrow mechanism. On the drug Ibrutinib there is what I think is a diphenyl ether. I know that the Williamson Synthesis can be used to form ether but I do not understand how to form a diphenyl ether at all. I tried looking up the Ullmann synthesis but I am not sure if that would be the correct way to form a diphenyl ether. Could anyone please show me how/ what reaction would occur that would form a diphenyl ether on Ibrutinib? Any help or suggestions would be very much appreciated. Thank you! http://www.chemspider.com/Chemical-Structure.26637187.html I have attach…

Hi. I am currently doing a research project on synthesizing a water-soluble rotaxane via Diels-Alders reaction. But I am facing a problem in synthesizing this molecule(please refer to attached photo) which is part of the process to synthesize a dienophile for Diels-Alder reaction. I anticipated to be able to synthesize compound 17 from compound 16 via hydrolysis of the methoxycarbonyl group, but it went unsuccessful. I think instead of the methoxycarbonyl group, the maleimide group underwent hydrolysis. Are there any ways to resolve this issue? How can I hydrolyze the methoxycarbonyl group under the presence of maleimide?

Is phenacetin considerate to be a little polar or extremely polar?Thank you

Hi I'm doing a lab with TLC and I have a polar TLC plate and a polar specimen. I know that because of those two being polar, the migration of my sample will be reduced, but if I use a more polar solvent for my mobile phase, will this increase the migration or reduce it? How does the polarity of the mobile phase affects the migration? Thank you.

I'm trying to conduct an experiment to extract caffeine from tea, using dichloromethane as the organic solvent to extract caffeine and sodium carbonate to separate out the other organic chemicals. The question here is, are there organic chemicals in tea (e.g.catechins, saponins) that would not be affected by the sodium carbonate and get mixed up with the caffeine in dichloromethane? If so, what else could I use?

Hello everyone! I struggle to find a way to create a diester (carboxyl group ended) from dicarboxylic acid and diol reaction. I know that when the reaction between two is acid-catalyzed the polycondensation occurs with creation of polyester. I would like to stop the reaction with A-B-A product (where A is coming from a dicarboxylic acid and B - from diol). Could someone help me with that?

So I had a stock of Sigma 9-bromofluorene I planned to use to generate some new chemical antagonists. Problem is that the TLC showed 4 spots. Ordered fresh stock, still came impure. Issues with Sigma aside, I need the compound so I just ran it through the biotage...TWICE...and it’s still not completely pure. The second purification did yield only one spot, but the NMR was not clean and being a student I’m not familiar enough with spectroscopy to determine where these peaks upfield are coming from. I’ve included the NMR (CDCl3) and maximization of the troubling peaks at 1.25 and 1.5. Though I’d usually assume 1.5 to be water, this was after a flash purification in 1% EtOAc…

Ok, let me preface this by saying I do not intend to actually carry out any synthesis of any substance. I’m a biochemistry student and I’m extremely interested in the “dark” chemistry. I’ve only taken chem 1 & chem 2 so I wouldn’t even have the knowledge or experience to actually synthesize anything. In addition, being a college student, I definitely couldn’t afford the materials to do this. I’m genuinely interested in the science behind this and I can’t find a clear answer online. This information will also serve as part of my extra credit assignment! So any information would be great Ok now onto the question: So, with my limited knowledge of organic/synt…

Someone I work with told me that water is not wet. If this is true that's the simplest way to fully understand this?

Hi everyone, I have a homework in organic chemistry and I really don't know how to do it so I would be delighted to have your help Here is the exercise : The synthesis of aspartame is carried out according to the following scheme: In a first step, the action of methanol in the presence of hydrogen chloride (HCl) gives compound A in which a single carboxylic acid function has been esterified. This compound A is then reacted with phosgene (COCl2) to give the cyclic product noted B. Propose a mechanism for this transformation from A to B, knowing that phosgene can be considered in this reaction as a double acid chloride (Cl-C(O)-Cl).

Hi, I wonder if someone could help. Im currently an undergraduate student and my organic chemistry is not good and I would like some advice with a reaction mechanism. I am trying to work out the reaction for the cyclisation of creatine to creatinine in acidic conditions. All I have been able to find online is the first image. My apologies of there is nothing else too this and that is all there is too it. I have been trying for a while to figure this out, one pathway I have attached below but I can see this is wrong but its the closest I can seem to figure out the would depend on the H+ ions in acidic solution. I know i'm probably complet…

I am doing some research into how hylauronic acid becomes cross-linked using BDDE. I have a few question around this issue. - Does the BDDE become the link between the 2 molecules or does it just facilitate the molecules connecting, i.e connect the molecules then move on unchanged from the original BDDE. Similar to an enzyme. Or does it become the link? - If this is the case, are their any other products of this reaction other than just the cross linked hylauronic acid?

What's the reason for substituting acetone with EA? Is EA more green? Cheaper solvent to produce? Just curious..seems unnecessary..but then again I don't know all the facts. ~ee

Hello, i am in my second year at university, studying chemistry. In this year's laboratory, our professor told us that we should make a compound of his choice. He would not help us at all saying that we learned enough the past year in order to pass this course(he would only let us start the experiments if we show him a good synthesis plan for the compound he gave us). So i found some steps that seem to be fine at reaxys and the professor told me its okay to start. At my last step i need to do a reductive methylation and add 2 methyl groups on an amine. I will use formaldehyde, the amine will react with a schiff base reaction and i will get an imine. Then i use Sodium cyan…

In a lecture I recently watched there was an example of using the Eyring equation. I have attached a picture showing the values plugged into the equation. The activation energy is 27.2 and the temperature used is 298 K. The answer given in the lecture is 7.0 x 10-8 for the reaction rate. I have tried to work this out on a calculator but can't get the answer given? Maybe I am multiplying the wrong values together. I found an online calculator tool which came to the same answer(2nd screenshot attached) Any help would be appreciated.

I want to use acetic acid for weed control, but the 5% food grade stuff doesn’t seem to be acidic enough to kill most of the grasses growing in the sidewalk joints. What would the best way to concentrate it so that I have 1-2 liters of it at 20-30%?

Can someone help me with this reaction schemes?

Chemistry help How to define the melting point of a mixture, which is composed of substances having different- different melting points?

Is there a reagents or mechanism that allows you to displace or get rid of a methyl group attached to a sp3 carbon like taking away the methyl group from methylcyclohexane? Of aromatics, my understanding is the methyl group in toulene cannot be removed because it would disrupt the benzene ring which is very stable/low energy

Secobarbital has a logP value = 2.03 an so is not soluble in water. However, looking at the logS/pH graph on chemicalize, it is marked "Solubility category: High". Thank you in advance.

do people create a chemical bond when touched?

I have tried to react sodium salt of aliphatic as well as Aromatic sodium carboxylate with non branching primary alkyl bromide. Solvent was ethanol under reflex conditions. I am only get my reactants back?! Can any one tell me what's wrong?