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Josh512

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  1. Hi everyone, I have a homework in organic chemistry and I really don't know how to do it so I would be delighted to have your help Here is the exercise : The synthesis of aspartame is carried out according to the following scheme: In a first step, the action of methanol in the presence of hydrogen chloride (HCl) gives compound A in which a single carboxylic acid function has been esterified. This compound A is then reacted with phosgene (COCl2) to give the cyclic product noted B. Propose a mechanism for this transformation from A to B, knowing that phosgene can be considered in this reaction as a double acid chloride (Cl-C(O)-Cl).
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