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About Function

  • Rank
  • Birthday 12/27/1996

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  • Location
  • Interests
    Movies, music (where shall I start ...), neuro-oncology (with special interests in gliomas), neurology and neurophysiology (with special interests in epilepsy and (problems of) consciousness), endocrinology (with special interests in fertility, andrology, and endocrinology of the adrenal cortex)
  • College Major/Degree
    BSc in Medicine
  • Favorite Area of Science
    Medicine: neurology, neurophysiology, endocrinology
  • Occupation
    2nd year graduate student - Master of Medicine

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  1. If you're doing an MD, publishing opens doors to further specialisation.
  2. The news about that black hole thing made me think. Now forgive me, physicists and others, for being such a noob when it comes to astronomy, but I had this idea, which didn't sound too stupid to me, but again, I'm a real layman in astronomy.

    I was thinking that the big bang may have been a black hole, being overloaded with everything else the universe held, such that it became unstable, and exploded? Additionally, if I'm right, black holes grow while eating stuff, and may eat each other. What if our whole universe will come to a point in time where there are only two black holes, which have eaten anything else, remaining only for one to eat the other one, leaving only one giant black hole, once again being overloaded, and exploding, like a new big bang?

    1. StringJunky


      No. Stick to medicine.  :P

    2. Strange



      Moderator Note

      This is not appropriate for a status update.

    3. peterwlocke


      that is a STRANGE thought.

  3. In the hospital environment, a lot of letters must be written. I'm looking for a way to standardize all letters I'm making. To do so, I would like to make a MS Office Word wizard, which just asks me all relevant things (e.g., salutation, patient name and birth date), lets me select all things in clinical examination that are deviant from a list ..., and then merges everything into a standardized document, which would be a bit easier than making a template.

    Does anyone know how I can do this?

    1. koti


      There is a whole vertical IT industry dealing with adressing what you wrote plus much more. There are specialized genre of software dealing with medical needs alone, those include everything from ticketing, registering a patient, printing stuff, keeping dynamic databases accesable for different pieces of software and a lot more - everything that needs to be done to fulfill any medical environment. Its a competive market where everything that needs to be provided has been provided, I would suggest you look into talking to your hospital IT guy...I know he presumably might not be too hot as IT guys tend to be not too interesting but hey, you gotta deal with it :P 

    2. peterwlocke


      i hope they are not incompetent but they probs not cause hospital.

    3. fiveworlds


      You can use vbscript for that. I dunno why you would though since as koti says there is plenty of software available to do so. Google it and see if you can find a software that suits, if not ask your it guy or somebody here could type it up I'm sure.

  4. For once, I passed all my exams with great distinction, and my thesis specifically with greatest distinction ^_^

    Let's hope my internships (starting March until July 2020) can help me finish my Master with great distinction ...

    1. Show previous comments  7 more
    2. Function


      Don't know about the States, but most hospitals here don't generally run for profit.

    3. peterwlocke


      oh. that is odd. but kind of cool.

    4. peterwlocke


      can you post thesis link?

  5. Defended my thesis in front of the examination board. They were very pleased, found both the thesis and the presentation excellent, appreciated my direct and to-the-point answers to their questions ... Couldn't ask for more! 8 February is verdict day ...

    1. Show previous comments  3 more
    2. peterwlocke


      I can't tell if you are serious or not.

    3. koti



    4. peterwlocke


      you see i find that worrying. 

  6. Supervisors were happy with my thesis, said it could easily be a PhD dissertation :lol: to be defended on 21 January ...

    1. Show previous comments  1 more
    2. MigL


      Good job.
      Make us proud kid.

    3. Function


      Not at all, Eric. Exams coming up. Already got two, and still have to pass 7 in January. Fun.

    4. koti


      Think of all the beemers youre going to buy as an MD, should help with exam studying :D 

  7. First full version of my thesis complete! To be revised by my supervisors, and to be printed :wub::lol:

    1. studiot


      That must be a weight off your mind.


  8. Missed those allegedly self-conscious flippin' creatures. My bad.
  9. Please, give solid arguments why you think that. Above all, humans and higher primates are thought to be the only species to enjoy sex, and not only do it for reproductive purposes. So imho, this statement becomes false.
  10. Concerning type 1 errors: each patient had received a MR spectrum. Each spectrum had some characteristics (11, to be precise, of which 1 was categorical, the other ones continuous), which were all subjected to Shapiro-Wilk (in each subgroup per comparison), and variables with allegedly nonnormal value distributions were log-transformed, and the test was run again. And then, all variables were compared each time between 2 distinct groups (e.g., high-grade tumours v. low-grade tumours). I applied a Bonferroni correction in post hoc tests where more than 2 tumour categories were present (e.g., grade I v. grade II v. grade III v. grade IV), or when the categorical variable (which had 3 categories) turned out to be significantly different between any two (or more) groups. Post hoc chi-squared or Fisher's exact tests were then run, with Bonferroni correction applied to the significance level. For the other analyses, there was no need for type 1 error correction, as one could interpret each comparison to be a separate "study". Additionally, no variables were ever combined into one predictive model. That would have led me too far. I'll look for some articles that are representative for in vivo MR studies.
  11. There are differences in other parameters within comparisons of other groups, but for this one group–group comparison, only this variable differs significantly. I already implemented everything that’s usually used as parameters in MR spectro in human brains, but thought of ‘designing’ new parameters. Edit: after all, I aimed not only to confirm what is already known, but to develop some more unusual variables, as we are in search for optimisation of noninvasive diagnostic methods in tumour assessment
  12. I am looking at the entire spectrum, but certain frequency peaks represent very distinct metabolites. Change in protractor direction, would that actually not be exactly the same as adding 90 degs to every measured angle post hoc? And that’s the stupid part: a nonparametrical comparison of the original angles does not differ significantly between 2 groups, whereas the Briggs log of the angles + 90 degs does. And as my thesis actially focusses on tumour group classifications, I wouldn’t just consider this as a methodology designed “just to find something significant at one point”, but as a methodology to find and describe class predictors. First step in such process is assessing differences in parameter distributions between both groups ...
  13. Log and square root transformations are common transformations in statistics for variables that are nonnormally distributed, hoping to achieve normality in their log- or root-transformed variants. Which I got. IBM argues that it is possible to "add a constant big enough" to all values, such that no value is negative or zero, and then apply log transformation. An advantage to this method would be that simply adding a constant to each value does not alter variance amongst variable values. The situations you present are highly unlikely. We're talking about proton NMR spectroscopy of some in vivo metabolites. Achieving the situations you suggest are nearly impossible, as the peaks themselves will just stay where they are, and only chance in amplitude, not in frequency/chemical shift, which is displayed on the horizontal axis.
  14. Because that's how I defined my angle. It's always defined as the angle the line (or, if you like, vector) from the first to the second peak makes with a horizontal line. I wouldn't have liked working with (360° - (negative angle value)) to substitute the negative angles, as then I would have to conclude that the second situation would have a larger angle, which, according to the definition I gave to that angle, is absolutely not the case. The sign of the angle is inherently correlated with the characteristic of both peaks relative to one another (first peak higher, or second peak higher). The constant arrangement of both peaks on the horizontal axis made me define the angle to be indisputably either greater than -90°, or smaller than 90°. "Log transform a variable" is performing a natural Briggsian logarithm on all its values, and saving the results as values of a new variable.