Organic Chemistry

Firstly, I'm sorry if I'm posting in entirely the wrong place - I'm writing this at the suggestion of a pharmacist who couldn't help me any further with an important question (neither could my health specialists). Context: I may have a food intolerance/sensitivity to 'amines', and I'm currently on a supervised elimination diet with a dietician to determine if this is the case. I'm also prescribed dexamphetamine as a treatment for ADHD. I have a (difficult to confirm) suspicion that I react to this medication, but my psychiatrist said he has never observed the symptoms I show in response to this medication. My dietician was unsure if the amines in foods & the am…

How to synthesize phenibut (β-Phenyl-γ-aminobutyric) from gaba (γ-aminobutyric)? I hope I won’t violate any rules. It’s legal and just a question:) If I have gaba powder, is there a way to make it to phenibut? (It’s a legal supplement in my area). It’s the same molecule, only a phenylering is added. I can’t find a way on the internet. Is there a way to bind (Benzol?) it to gaba? [phenibut](https://en.wikipedia.org/wiki/Phenibut) [gaba](https://en.wikipedia.org/wiki/-Aminobutyric_acid) [picture of the molecules](https://de.wikipedia.org/wiki/Datei:(%C2%B1)-Phenibut_formulae_V.1.svg)

We have a tertiary-butyl protected amino acid in which nitrogen is protected with FMOC. We removed the FMOC group with diethyl amine, and we used rotary evaporation plus a toluene strip to remove the volatiles. We attempted to purify over a short column of silica. We were able to remove a fast-moving impurity (presumably dibenzofulvene or a derivative) using 40:60 EtOAc/hexanes, then switched to 99:1 hexanes/TEA in the hope of eluting the N-deprotected product, still bearing the carboxylate protecting group, but the product was not soluble in EtOAc or in DCM (it might have been a suspension). We eluted with 90:10 DCM/methanol and saw two products by TLC. They were no…

For anyone looking for an organic chemistry game of the wordle family style, I'm currently working on OChemdle: https://organicchemmaster.com/chemdle

What are geometric isomers? iv'e been having trouble understanding what they are and what they are for.

Would a "non-fluorophore" emit the same amount of light absorbed/not emit a photon after absorbing light? Basically, how would a non-fluorophore act differently from a fluorophore? Also, do scientists use Stokes' shift to determine whether something will shine under a UV/Infrared light? If so, how exactly? Why do fluorophores have to be cyclic/have high resonance energy? Why do fluorophores bind to nucleic acids? I know they help detect stuff, but why would a nucleic acid anf fluorophore organically bind together? Any responses to these questions would be great; I'm sorry if I used the wrong terminology — I'm not an expert.

Hello. Ive read about a technique used by ms13 to smuggle drugs and was wondering. Out of sheer curiosity. What chemical can you mix heroin with in order to make it fully liquid without it losing its properties? Furthermore. They dip clothes in this liquid. How would you extract only the heroin from such a garment. Thank you:)

Is it possible from diethyl(phenylacetyl)malonate to make phenylaceton and how? Thanks in advance

Good day. Perhaps will be better in other subforum, please move as deserved. Food can be analyzed telling its amount of protein, carbohydrates, fats, minerals and all the components ingested and their weights. If the body is not using/storing something by digestive, genetic or absortion defect, how is that to be determined ? Can a blood/tissue test tell if a person has deficiency of -say potassium- or -say carbohydrates- , even with abundant enough consumption of those in food ? And the reverse, can some analysis tell there is too much -say protein intake- ? Is there a recommended percentage of the human body composition ? When I used to work in aquac…

Hi, I have been learning new things about Fluorophores (photosensitizers) and how they get conjugated to antibodies for cancer therapy (photodynamic therapy). And I have read something that I didn't understand: it says that the Fluorophore should be water soluble to be used in this kind of therapy (photodynamic therapy), but I don't understand why? What's the point of its water solubility? And what does it have to do with the effectiveness of photodynamic therapy? And what would happen if it wasn't water soluble? Any question that can be answered by you, I would be very thankful, cause I've been struggling to understand. Thanks a lot in advance.

From Wikipedia : Prototropy is the most common form of tautomerism and refers to the relocation of a hydrogen atom. on these Images you san see the four(4) tautomeric forms of a <TRIPLE-Base> !!!... FIRST !!!... IF you look only at ONE "Base" !!!... You can see the inside Hydrogens to move (Left/Right) from the one Nitrogen-atom to the near Nitrogen-atom !!!... of the same "Base" !!!... and that ist "Prototropy" !!!... SECOND !!!... IF you look now to the three(3) "Bases" !!!... Between two(2) Bases !!!... You have two(2) Hydrogens !!!... which can move !!!... BUT now !!!... they don't need to move (Le…

Hi I have opened a new bottle of nonafluoro-1-butanesulfonic Acid CAS 375-73-5. As per the storage instructions of the MSDS I blanketed the unused material in an inert gas (argon) before stoppering the container for storage. The unused material has gone from a colourless liquid to a pale brown colour after the gas blanket application. Can anyone suggest what is happening here please - I have two thoughts - the gas steam was not dry or the gas steam is contaminated with something other than argon (maybe oil from the regulator ?) Any ideas or experience would be gratefully received. Thank you

Why does green tea from Twinnings tea tag turn black when I add honey to it? I was making green tea from Twinnings brand, and I added honey to it, and it made the green tea turn dark color. What is the reason for this phenomenon? Or possible reasons?

I need to know how make auto fire bond what are the chemical used to ignite matchstick from some distance

https://doi.org/10.1002/chem.201101163 I am working on synthetic routes to a glucoside. The beta-trimethylsilylethoxymethyl (SEM) group has some attractive features (particularly in regards to deprotection), but I have only found one paper in which four SEM groups were used to protect the oxygen atoms at carbons 2-4 and 6 of a glycoside conjugated with a steroid. They did not deprotect to the best of my knowledge, but I assume that one would use a standard recipe. I did find a paper in which a glycoside was protected with several different groups, including one SEM. Are there disadvantages to using the SEM group as the protecting group? Are there reasons why it …

Dear Friends i need a help, actually im tring to remove stearic acid coating from calcium carbonate powder. Percentage of coating level is about 1.50%. I have used hot IPA to dissolve stearic acid and try to filter the solution. But my efforts remained unsucessfull. Please let me know if any other method or idea i can used. Thanks!!!

I know there are easier routes but the route below would enable a completely green synth starting from black pepper(which would be great for the insecticide industry to have it come from black pepper extract(piperine --> piperidine(or piperic acid) --> piperidone) from a marketing and environmental perspective. Also has tremendous application in Southern Africa due to rising import costs etc. Anyway pls feel free to ask anything(it's job related and I really need the help and I'm not getting anywhere myself inorganic chemistry is more my forte but I'm trying. I don't know how you guys just know this stuff like "oh just add a carbonyl group with some duck-tape". Make…

Fermentation.docx

Hi I'm making up a paint stripper that will strip enamel and acrylic paints from polystryrene models. After a bit of research into what's already out there I have come up with a mixture of isopropanol and butoxyethanol. It strips paint very effectively, quickly and doesn't harm the styrene, so job done. However I have noticed that these two alcohols tend to separate after a while when mixed together and I have heard that dimethyl carbonate prevents this separation. Question is, how much do I need in my 1:1 mix of IPA and BOE for it to do this? Regards Buntobox

Does anyone know how this reaction proceeds with the following reactants? Glacial acetic acid (i presume solvent) Cupric acetate monohydrate Ammonium Nitrate

Downstream Petrochemical Pumps is the flow of fluid towards the outlet of a pipe or any equipment you are considering conversely upstream is away from the outlet.

I'm placing this under organic because it pertains to Britains former colliery waterways. Is it possible to add Flocculants to Britains former colliery spoil waterways to rejuvenate them back to their original state ? I understand that soft rock on the British coastline will contain sediment, along with limestone, which will give the water a natural cloudy appearance, but there is still much colliery spoil that could be dealt with. There is a wonderful video here of something similar being done in a river bordering Peru and Bolivia : If it were that easy then surely the U.K. government (given the chemistry was invented by a British Ch…

I am working on a device to detect different elements in the environment. Right now I am detecting methane, carbon dioxide, and volatile organic compounds, but I also need a way to detect volatile fatty acids (VFAs). From what I have seen, VFAs produce carbon dioxide and methane, are there any other other "signs" that could be used to find these in the air? For instance maybe a certain concentration of alcohol or hydrogen, or maybe a certain change in humidity or temperature. Looking for methane and carbon dioxide looks like my best option, but I am not very informed about these fatty acids and I am not finding much online, so any help is greatly appreciated!

Can anyone identify this compound? Kudoos for quick answers.

People, I often wondered, about what happens to all the carbon compounds, primarily cellulose, from the "wood" of plants/trees after a fire destroys the plant. Isnt the product a combination of charcoal, or outright burnt wood/carbon? If so, isnt it true that such a state of carbon will not react in nature, since carbon is so difficult to react with any compound. Imagine- how can charcoal react to form new plant growth if it has been destroyed by natural fires/volcanic heat/etc over billions of years. The plants growth comes from CO2 in the air, then converted to cellulose, then burns up in a fire, and cannot react anymore(?). Doesnt that mean that eventually …