Genetics

Hello, I read about an autosomal recessive disease called "essential fructosuria", in which the enzyme fructokinase is absent and dietary fructose is phosphorylated by hexokinase to give fructose 6-phosphate. But why is this compound excreted instead of entering the glycolytic pathway? I mean, the third step of glycolysis is the conversion of fructose 6-phosphate (deriving from glucose) into fructose 1,6-bisphosphate, so why can't fructose 6-phosphate deriving from fructose be processed in the same way?

Suppose why the presence (U) in the system of cell-free protein synthesis containing poly (U), poly (A) and poly (G) does not determine the inclusion of 14C-phenylalanine in the synthesized polypeptide molecule.

hi! my eyes are hazel out of curiosity I would like to know in which countries are these types of eyes more common i am from France bye

I know there already is that topic but it didn't get any good answer so I hope someone here will answer. I have green eyes, pale skin (but I tan quite easily) and dark brown hair.

Who were the first Polynesians and where did they come from? One article says it was Tonga then on Wikipedia it says most scholars lean more towards Samoa. Who is the original Polynesians and where did they come from?

Hello everyone Just to make some things clear: Everything mentioned in here is mentioned from a scientific point of view and results from personal observations. This thread is not meant to be racist; if anyone feels in a more or less direct way offended by this post, please let me know what can be changed to work towards a solution that works for both parties. So I sat on the train today, after spending too much money on some sweets, a little reward to myself for successfully taking the exam on pneumology, haematology, and nephrology earlier today. Looking into my candy bag, and picking some sweets, I suddenly noticed a specific odour. An odour t…

Hello folks, I want to store saliva samples for a long time that is for more than 7 years. Different companies seems to offer different types of saliva samples. For example, some of them offer saliva samples testing for family background while others offer saliva samples for disease risk. Which type of saliva sample would be best for long-term storage of DNA at home? Have a great day and thank you in advance for answering.

This question is just out of curiosity. Does anyone know if it is usual for a person who has one unusual physical feature to have several? I am asking because I came across some information about the palmaris longus muscle, on Facebook, which I lack and supposedly this is unusual. I then got to thinking that I also have B- blood type (1.5%) of people, I had two extra teeth that were removed in childhood (hyperdontia supposedly unusual to have more than one and not have an accompanying syndrome), I have an extra rib, and I have a couple other abilities/attributes that are found in only 1-2% of the population. Do these things usually cluster in some people or should I …

Which of the statements below regarding the genetic code table is NOT true? (1) The table has 64 possible combination of triplets (2) All of the 64 codons correspond to 20 different amino acids (3) Every amino acid is encoded by one or more unique codon (4) Some of the amino acids are encoded by multiple codons (5) Organisms as distant as humans and bacteria share the same genetic code.

Can mutations that are able to be handed down to your offspring be caused by environmental factors and your lifestyle? Can you somehow cause mutations (which are favorable to you) to occur in your body?

Hi, I want to storage DNA in hair for at least 5 years. Does it affect the sample if I clip the hairstraws out with a scissor instead of pulling them out? According to the article in the link below one should pull the hair out: https://www.google.no/amp/s/m.wikihow.com/Collect-DNA%3famp=1 Thank you for reply.

Hi. in an article about "DNA Collection and Archiving" I read that hair samples could be stored in a silica desiccant dryer. I live in Norway, so I found a possible source of silica desiccant on a website called realmarine. They seem to have the following types of silica deisscant avilable: http://realmarine.no/produkter/torkemiddel-silica-gel.html Which one of the silica desiccants in the link below would be most suitable for long term storage of hair for at least 5 years? I plan to store the hair in room temperature. Thank you for answering.

I have many thousands of hours studying and researching emotions and their development. A critical role in emotional development is the process of bonding which is outlined in Attachment Theory. The principles I talk about are empirically proven. I find myself increasingly needing to explain them in terms of genetics to people who ask me to outline the principal of the process. My understanding of genetics is not professional, and I am insecure of the terms I find myself using and feel duty bound to use correct terms to form the most accurate description I can. I ask people who have a grounding in genetics to criticise the following paragraphs (which are my response to …

I recently decided I was going to start a non-profit organization focused on using genetic engineering to solve world problems. I believe I started on out the wrong foot though as they say. No one wants to discuss the link between genetics and IQ. Should I push through this taboo subject or leave it be and pursue other kinds of genetic philanthropy like modified food crops? Some part of me says I should confront this rather than shy away from it. On the other hand no one seems to be interested in having a discussion anyway and it could damage the image of the non-profit. Would it be ethical at all to increase IQ genetically anyway? I know we haven't done all the research …

Hello, in an article about «DNA Collection and Archiving» I read that hair samples could be stored in a silica desiccant dryer. Where can I buy a silica desiccant dryer? Thank you in advance for answering.

Backstory: My paternal grandmother had five kids however, there is some speculation that she had an affair many years ago during her marriage which resulted in two children (one of them being my father). My father is deceased and the person who may have been his father is also deceased. The person who my paternal grandmother was married to and claims is the biological father is also deceased. Commercial bought DNA kits (from Ancestry or 23andme) probably aren't the gold standard to assess these types of situations however, they're convenient (and relatively cheap for the realm of genetic testing) so it's likely my only option. Questions: 1. Since I am the child of …

For my schoolwork I am required to write a dissertation on something. I've been told to do it on whatever I am interested in taking a career in, so of course I chose genetics. My plan was to write my dissertation on the genetic modification of the human race, however I want to make sure I explore all of my options, which is why I am here. I have always been interesting in genetics, not for its power or its potential to better the world in which we inhabit, but instead, because of its fun applications and bizarre possibilities. Anyways, What could I do my dissertation on? Also, instead of a dissertation there is an option to present some field work in the form o…

Hello every one I was asked with the study a Transcription Factor X, and the have mouse modified genetically, as KO/KO = homozygous knockout; KO/WT = one KO allele, one wild type allele; TAD/TAD = homozygous for deletion of the transactivation domain (TAD); TAD/WT = one allele with TAD deletion, one WT allele; TAD/KO = one allele with TAD deletion, one KO allele; DBD/DBD = homozygous for point mutation inactivating the DNA binding domain (DBD); TAD/DBD = one allele with TAD deletion, one allele with DBD mutation These mice show: KO/KO = no phenotype; KO/WT = no phenotype; TAD/TAD = dramatic phenotype; TAD/WT = mild phenotype; TAD/KO = dramatic phenotype; DBD/DBD = no…

Hello. Where can one get testing kits for at home gene storage? So that one can store genetic material at home. Thanks in advance.

What is the most possible gentic method to make people live much longer?

Is there any research on positive physiological changes do to childhood abuse?

I'm reading this article on CRISPR used in human embryos, https://www.wired.com/story/crispr-base-editing-first-china/?mbid=social_twitter and it says and I'm wondering, if the exact same thing was done in all the embryos, why do you get different results in some?

Hello Is it possible that this type HLA-B27 can be altered, snipped, cut, edited, replaced, switched off in the human body ? https://en.wikipedia.org/wiki/HLA-B27 This is a common gene highly implicated in many diseases of the immune system...one way or another taking it out of the equation I would hope be life changing for the positive if a way could be found. Trying to find out for my own research ..as someone who suffers from the gene...as do many. If it is possible or not please could the reply take the time time to explain as much as possible the reasons for or against the possibilities. Thankyou.

Scientists have discovered that the deteorioration of the tightly-packed bundles of DNA that are responsible for our normal cell functioning is actually reversible, and figuring out how this process works could enable new treatments for age-related diseases like Alzheimer’s. What I would like to brainstorm in this forum, is where to start if one would like to implement or somehow imitate the process that the turreptosis jellyfish undergoes when it renews it cellular structure to never die. I know it is very difficult or perhaps even impossible to attempt equating the way this sea creature’s biology functions in human bodies, but I would like to seriously postulate th…

Its is often stated that we share 98.7 percent of our DNA with chimpanazees which appears to be rejected now (not in the sense the data wrong, however that the method used wasn't the best). I found in this article that we share 95% https://www.scientificamerican.com/article/what-does-the-fact-that-w/ yet on another 96% https://www.ft.com/content/43445728-1a44-11da-b279-00000e2511c8 and even other estimates on other websites. Is there an agreed upon percentage among geneticist as to how much DNA we share with chimpanzees?