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Alfred001's Achievements


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  1. I was not implying with my question that a person's politics can be reduced to their IQ and that's not something I believe. I'm just curious about whether there are differences. I DEEPLY, DEEPLY appreciate that and commend you for it. In my view, keeping one's personal politics out of apolitical discussions (this topic is tangentially related to politics, but it is not politics that is the topic) is a matter of basic civility, yet it is violently violated constantly today. I've had people slap me over my political views in music reviews. Pardon the soapbox moment. Thank you!
  2. Is anyone aware of any studies looking into the IQ of various political groups? Just left vs right would be interesting, but if there's a study that slices the groups more finely than that, that would be even better.
  3. I've heard so much conflicting information on this topic and it seems like there are studies to prove every position you want to take on it. The most popular view seems to be however that the standard surgical masks that people most frequently wear stop you from infecting others, but don't protect you, whereas there's some other type of mask that protects both you and other people, is this in fact what the science suggests? What kind of protection do the cloth masks provide?
  4. Physicsts known to the general public are rare. Newton, Einstein and Hawking would be known to everyone and then after that, at a lower level, you got Feynman, who would probably not be known to everyone, but a lot of people with some interest in intellectual topics would know his name. I'm sure there are a lot of physicists with great achievements whom no one in the general public has heard of. You'd probably be hard pressed to find a person who's heard of Ed Witten and I'm sure there are great physicists yet more anonymous. Now, supposing Feynman had never written any popular science, how well known do you think he would be? He appeared in a lot of television programs, but would that have happened if not for his popular books? Do you think he would be another anonymous physicist or would he be somewhere close to his current level of popularity?
  5. Well, that's a little glib, exchemist was making a valid point and I'm curious whether the point can hold up when evidence is examined. The point being that, yes, advanced maternal age increases the chance of chromosome related issues, but is it so that children of older mothers who do not end up having chromosomal problems will suffer no negative health effects relative to children of young mothers. Or, in brief, does maternal age make no health difference if a chromosomal issue doesn't happen. Does anyone know whether there's evidence refuting this hypothesis? Now, John Cuthbert referenced a study that shows non-chromosome related health effects, but the study is in rats. It's not nothing, it shows that at least in rats there can be some non-chromosome related mechanism, still it's not humans.
  6. I won't press this any further, thanks for the responses and the patience. Let me just ask you something unrelated to the vaccines, if we can take the thread on a very brief digression and if this is a topic you know about: This business about eliminating lipids got me thinking about something I've often wondered (and worried) about, which is mercury in fish. You'll usually hear that you SHOULD eat fish, but not more than x servings of such and such fish a week. Is that because if you don't cross a certain threshold of mercury in a given time it will get eliminated without having an effect, whereas if you go beyond that it doesn't get eliminated quick enough and could have some negative effect?
  7. I thought that the forum might automatically display the links as tweets, as it had done with some of the earlier links I posted, that's why I just left them as tweets. This is what the first link says: "Tissue to plasma exposure requires calculation of AUC. The sample period did not go out long enough to calculate it since the Cmax looks like it occurs at >48h . Typically these studies measure out to 7 days." To be honest with you, I don't even fully understand what they're saying, but they seem to be referencing the fact that peak values for some of the organs are reached after 48 hrs, which did not permit the calculation of AUC, whatever that is. So, my question with regard to that is just if you could explain to me what the person is saying lol The other two just ask why the lipids are ending up in the ovaries and bone marrow and whether those organs can clear them, but I guess you've answered that, although you didn't specifically address bone marrow, I don't know if anything different than what you've said about the other organs applies to it.
  8. But if that is the reason, I don't understand why they monitored for 48 hrs only. And there's this: https://twitter.com/TailFirefly/status/1404474619923476484 Ok, I take your point, but what about this: https://twitter.com/mrich0312/status/1404399263975608320 https://twitter.com/Wildbranch/status/1404421593049321475 Do the ovaries and bone marrow qualify as inert tissues that you mention might not clear the lipids? To be clear, this is not a rhetorical question, I don't know whether they do. The adrenals also show just a steady climb through 48 hrs. Well, I'm not worried by the fact that they did these studies, I DO accept that this is the standard approach (except, as it turns out, why only 48 hrs), it's more the results that worry me, although I accept your point about liver concentrations not being a cause for concern since it's the filtration organ. It's the bone marrow, ovaries and adrenals that worry me. Now, again, if you tell me that it's known that those organs clear them, too, I'll accept, but I have to ask the question. Yes, although I'm not sure what you mean by the values being established. The rate of elimination? Yes, that does assuage my concerns quite a bit. I am not set in my beliefs at all, in fact there isn't anything I DO believe yet about this, except the points I've said I accept.
  9. Well, if it's a foregone conclusion that the LNPs are gonna get eliminated, I don't understand why they measured how much of them gets accumulated in the various organs to begin with and if mRNA is terribly unstable and is only gonna stick around for 2 days max anyway, why did they bother to track where it goes? I don't know enough to know who has and hasn't got expertise on the matter, so I have to ask. What I know is that he's engaged in a debate with three people on Twitter who do seem to be acknowledged as experts in the filed and none of them have been able to refute his concerns. Again I have to ask, if there's no such concern, why did they measure where the LNPs end up to begin with? If it was simply sufficient to measure excretion routes, why did they measure this stuff at all? And doesn't excretion only tell us that the stuff is being eliminated, but not where from? So it doesn't rule out the possibility that there's somewhere where it's not getting eliminated from and where maybe it would stick around longer. And, again, I don't have any expertise on this topic and I'm merely asking questions because I want to get educated on the topic, so I don't understand why you have to be hostile about it. I'm not claiming expertise, I'm not claiming to know better than you, I'm asking.
  10. The discussion has kept going on Twitter and it seems like Chris Masterjohn has been able to poke holes in any refutations of his concerns. The discussion has branched off into too many threads to catalogue here, I'll just post one tweet and anyone interested should look back through the tweets to find the various threads branching off at various points (or go to Chris Masterjohn's timeline and look at his replies, that may be even better): https://twitter.com/ChrisMasterjohn/status/1409220193683976192 Ok, now, let me try to argue with you based on some of the stuff Chris said on Twitter: 1) Here's his objection to this argument https://twitter.com/ChrisMasterjohn/status/1409224095011590146 Now, this would not be applicable to your point if when you said "test mRNA" you were referring to some other experiment they performed than the one discussed here involving luciferase mRNA. Perhaps you're talking of some experiment where they used test mRNA which is known to have similar stability to the spike protein mRNA, IDK. 2) I'm not sure what you mean by "between say hour 2 and 48 h we see a loss of ~30% of the total signal," the value for liver goes up in that time. Or are you referring to the cumulative value for all the organs? You say that there appears to be a steady state with elimination balanced out by additional accumulation, but the only timeframe where we see a drop in value that we could take to be elimination is between 8 and 24 hrs and then the value goes up again at the 48 hr mark. Granted it only goes up by 1/5 of what had accumulated in the previous 24 hrs, but we don't know what happens after this very short time frame of 48 hrs and the last observed change is in the upwards direction. That said, you could be right, it could be that if we had data for an additional 48 hrs that we would se see-sawing and basically a steady state, but that's a hypothesis, we don't know for sure. 3) Well, as I mentioned in relation to 1, we can't be sure the mRNA is gone in 2 days, but also there's the issue of lipid accumulation and I'll post a message from a different covno I'm having where someone mentioned evidence that they might not be being metabolized (and this bears on 2, as well and your hypothesis that they're being eliminated):
  11. But what about their accumulation in other places like adrenals, ovaries and bone marrow? What do you make of the concerns expressed in this thread? His concern is (and I'm a layperson, so I hope I don't mess it up) that they only studied up to 48 hrs and at that point the LNP is still accumulating in the ovaries and adrenals, so we don't know what happens beyond that point, how much accumulates. He also says accumulation of the protein and the mRNA wasn't even tested and he's concerned about that, too.
  12. But what about the point about the possibility of accumulation of the protein or the vaccine in ovaries, adrenals and bone marrow?
  13. I think you mistyped something in the last part of the sentence, could you clarify?
  14. You often heard about how a mother being advanced in age is bad for the child she is bearing and I'm wondering, is that exclusively because it raises the risk of miscarriage or are there actually negative health effects that are passed on to the child as a result of the mother's age and what are the negative effects specifically?
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