Organic Chemistry

Hello, today I write my first post in this forum regarding a preperative HPLC system which I recently found. It is considerably cheaper than any other offer I could get. Does anyone use the ECOM ECS 12 system in routine prep. HPLC? Can you recommend it? I would be glad to get some feedback. Thanks everyone. Simon

I am currently studying for an organic chemistry exam and I just couldn't come up with a solution to the following question: Consider the reaction of 2-Propen + Br2 with water as solvent. Why will the nucleophilic water molecule add on C-2 and rather than on C1 of the Bromonium-Ion? The answer seems to be, because in the transition state the bonding between Br and C will dissociate quicker than the bonding between O and C will form, which leads to a positive charge on that C-Atom in the transition state and therefore water will add on the more stable "carbokation-like" carbon. My question is: why does the Br-C bonding dissociate quicker than the O-C bonding forms…

Hello everyone, happy to have found this forum! My name is Natali. I was wondering if anyone could give me ideas/suggestions on how, in general, to remove capric acid (caprate) from estrenes? Thanks for any help/suggestions.

Need to know exact mechanism and absolute stereochemistry? This is a beta-gamma unsaturated ketone and we haven't discussed them in class at all. I might be a little tired in the head (exam coming up), but this can't simply be a protonation of the double bond, followed by a nucleophilic attack on the formed carbocation could it? Does anybody have any tips on what type of reaction this is?

I am trying to mix BPA with epichlorohydrin to make DGEBA, but BPA is not soluble in epichlorohydrin.

Hey all im doing a project where I randomly select and synthesize a chemical starting from chemicals starting with the letter A all the way to Z and my first pick is acetonitrile im am choosing the chemical to be synthesized at random (or taking suggestions) and will likely require some help from patents and you guys so if anyone has a method they would like sharing that would be nice. I am an amateur hobbyist with no formal training My equipment consists of a 2l heating mantel A 2l rotovap Chiller Circulating water pump A fairly complete set of 24/40 glassware A ventilation system And a small aray of reagents....

Hi, I am trying to make epoxy resin and it has Bisphenol A diglycidyl ether in it and I can't find out the ratio between Bisphenol A and Epichlorohydrin.

Hello Everyone, I’m by no means a chemist, but I have been trying to learn a little bit about it, for a project I’m working on. I don’t know where else to ask, so I figured this forum might be a good place. I have an aquarium, and I am trying to calculate how much co2 is dissolved in the tank. If I understand properly, I can permanently put an upside down cup in the water, and use Henry’s Law to figure this out. Attached you can find a drawing of my set up. I can also use Antoine’s equation compensate for temperature Here is what I came up with, but I don’t have enough knowledge to know if I’m doing this properly can someone se…

Hi everyone. I've tried to make this solution with these chemicals. The two problems I've got are the dissolution of vitamin E (first, it dissolves in alcohol but when mixing in water phase, it gets separated again) and the adhesive of product solution when tested on the skin, it's quite uncomfortable until the skin gets dry. Please give me some instructions or method (same as the content shown in the paragraph “method” in the image below) for preparing the sanitizing solution (for hand wipe). Active Ingredient: Benzalkonium Chloride: 0,13%; Inactive Ingredients: Aqua; Isopropyl Alcohol; Glycerine; Tocopherols; Decyl Glucoci…

Hi, I'm curious to know why adding an O-H to the end of a molecule can, or will, increase the boiling point of the molecule. How can this happen? What goes on when an alcohol group is added?

why does the fragrance of the perfume last longer if we spray it on the part of our body where we have applied non fragrant lotion or vaseline?

Good day, I was hoping someone could perhaps help me in order to give the molecule below an IUPAC name. I tried starting using the molecular formula first however I did not get any search results nor do I know about naming 3 adjacent Cyclo chains. Please may someone inform me the process of naming this type of compound and how you got to the IUPAC name. ANY HELP WILL BE APPRECIATED

When explorers eventually reach Titan, I suppose they could take some farm animals with them which if they had enough to eat would create manure, although I'm not sure how pigs and cattle would get on in the low gravity (flying pigs?) But would there be enough minerals lying about on the surface to use as soil to grow crops? Would there be enough nutrients in it? Titanian wheat and potatoes?🙂

I keep getting configurations of M,N and O that are different from the model answer. I have no idea where I went wrong and I can't seem to make sense of the mark scheme. Any help would be much appreciated! The answers I've got: M : (R, R) N: (R,S) O: (S,S) The mark scheme:

I need help figuring this out. Thank you

Hello. I am struggling with a problem. I have attached it. I cannot rationalize a reasonable mechanism for the transformation of the reactant to the production shown. The initial problem is given at the top of the image. Thank you for any assistance. I have tried to protonate the -OH group and then have an enol kick out the water to form a carbocation; I've tried to make the enol at the top of the right ring make a 1,3-dicarbonyl and close the ring on the carbon adjacent to the initial OH group... none of these are working. Please assist! Thank you in advance.

why is the compound non aromatic despite it having resonance?

Hi all. DEET has been the champion since a long time. Some 'essential' oils follow with a degree of wizardry and old lady tales included. Recently, the clothesdryer sheets. What has worked for you, and even better, were you able to produce it at home with simple chemicals ? Heard about vinegar, alcohol, cinnamon, lemon peel,... Ignore 'natural', 'green' , 'healthy' , just what really works. What about soybean oil as main ingredient at a million percent markup ?

So having built Polyethylene and Polyethene from molymods I am left with 2 free Carbon bonds which I an use to chain them together. Just tried to build PolyPropene and just have 1 free carbon bond, so I can attach to a 2nd polypropene (included the info graphic for reference above) Am I doing something wrong or does polymerisation work differently for different types of monomers. I am kinda learning as I go along and making blog posts, the end game is to gain a basic understanding of this, enough to help in schools, it just seems interesting what I am finding. After posting an initial video to Peertube ( like you tube but decentralised ) it was sugges…

Hello dear friends! Here some thoughts and ramblings about an expert system seeking syntheses for organic compounds. ---------- Expert systems were among the first successful developments of artificial intelligence decades ago, well before machine learning https://en.wikipedia.org/wiki/Expert_system You can imagine them as a renunciation of the too complicated "if then else" control on the programmes by the programmer. Instead, the expert system comprises a knowledge base, that is a set of rules, possible actions applicable when their conditions are met, and an inference engine that has often zero knowledge of the topic but tries to apply billions of c…

Hi I am trying to write some tutorials on molecular modelling and making some videos to help me. Looking at Polystyrene do i build a benzene ring for that part of the molecule then attach the rest to that As in six carbon atoms e 3 double bonds and 3 single bonds and 5 hydrogen atoms as the sixth is replaced with the C2H3 component.? As part of this series I am linking to here so people can ask for help on science related issues. So fingers crossed we will get a few more people on the forum. Thank you in advance for any help . Paul

so the decreasing order of -I effect is NO2>CN>F>COOH>Cl>Br..... In chloro acetic acid, chlorine pulls the electrons towards itself rather than COOH, why? isn't COOH more strong than Cl? please help me out!

Can someone please help me with understanding how this works? I undestand a bit, but don't get why for example the a) is a "R" configuration? and not an S, because I think that "COCH3" is first then "HO" is second and third "CH3" So this in my logic should be S. Can someone help me understand why is "HO" first? If you want to comment also the other ones, please feel free, it will help me understand faster. I have the result, just I don't understand WHY. I will be very grateful to whom would like to comment and help me with this. Thank You guy for your time and your help.

As shown in the figure, 1)Due to SIR effect, the earlier delocalised lone pair of the nitrogen gets localised and therefore increasing basicity with respect to aniline. 2)Due to SIP affect the protonation of nitrogen in inhibited and hence basicity decreases with respect to aniline. which effect is superior or how do we determine whether the basicity increases or decreases? Please provide enough evidence to prove your claim/ cite good literature... a quantitative analysis of SIR and SIP effects will also be of great help... Any leads are welcome too... As shown in the figure, 1)Due to SIR effect, the earlier delocalised lone pair of…

is it possible to produce rubbing alcohol from alcoholic beverages?