Everything posted by CharonY
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Wheels in animals
Bacteria? Do mean something like flagella? In eukaryotes you can find functionally similar structures (though they are built differently) including eukaryotic flagella and cilia. However the movement is more like a beating undulation but those are actually involved in fluid movement (either moving through fluid or to move fluids).
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Got COVID, should I take anything?
Besides what others have said regarding the importance of boosters, monoclonal antibodies are mostly used in more severe or high risk cases. However, depending on where you are, they might not work anymore. Recent increases are driven by immune evasive omicron sub-lineages (e.g. BQ.* and XBB.*) against which these antibodies do not work anymore. There are also quite a few studies regarding longer term impacts on a range of health issues, including the immune system. So if something feels off, even a while after recovery, it is worthwhile to mention to MDs the previous infection, just in case.
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'Six Strikes & You Are Out ?'
I have heard an interview from the stupid caucus arguing that this is a good thing for tax payers as the government is now not spending money. Beside the obvious stupidity of the reasoning it is also a great way to argue that one's job is worthless (or even detrimental).
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What would be the most important thing than humans should try to achieve in priority in your opinion ?
Justice is at the heart of social reforms and there were good articles highlighting the connections between equity, equality and justice, though I cannot recall where I read them. With regard to children studies, I think most studies were aimed at fairness, rather than justice. The latter is more connected to a system that results in fair (or equitable) outcomes. I.e. if the system is set up to remove barriers that can lead to inequitable outcome. It does not mean the best (or optimal) outcome for everyone. It basically just means that a) there are no specific barriers to interact with a given system and b) that following those interactions, there are no differential outcomes based on factors outside of the control of the individual. Measures providing equity are stopgags to address inequality in the system. Justice means to remove the factors causing those inequalities in the first place and is much harder to achieve.
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Is 'Democracy' like 'Equality' ?
There is a bit of a problem with that, though. Equality in a democracy can not only mean equal access to voting (and already here we see discrepancies, depending on the system), but there are also issues in how equal power is distributed (or not). Countries without winner-take-all systems, including Canada and USA often struggle with over or under-representation of power, even if everyone is able to vote, for example. But even beyond that, the ability to exert influence over elections is vastly different. Here, you could say that we are all equal, as a billionaire's vote would not count any way differently than anyone else's. However, the ability to influence the outcome (so if we look at equity) it is very much different.
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What would be the most important thing than humans should try to achieve in priority in your opinion ?
This is also true for most policies. Societies and communities are changing in many ways (demographic, economic, technological etc.) so policies that had a known effect in the past may have slightly (or significantly) different impact at a later point in time. As such ideally the outcome of policies should be constantly monitored and evaluated. While much of that stuff currently comes from the right-wing ecology of the internet (they seem to be better organized in some ways), it should be noted that a lot of misinformation is a consequence of modern (social) media consumption and how algorithms are pushing outrage over information. It is not as such a matter of lacking education anymore, it is a deliberate system wit which facebook and co make their money. We are officially in a post-information age.
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Is 'Democracy' like 'Equality' ?
I think the democratic process, at least in its ideal form, hinges on equality. I.e. folks are at least theoretically given the same opportunities in participation. As such, it is focused more on process, rather than outcome. However, equity (i.e. adjustments to balance out systemic imbalances) are and have not been fundamental aspect of democracy. I would argue that only in fairly recent times it has entered the discussion at all. Historically adjustments to the democratic process were focused almost entirely on the equality aspects (e.g. enabling women to vote, or before that allowing men to vote regardless of income).
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Making some ethanol... [only for when you are reaaaaally bored !]
I found it interesting that in Europe there are varying limits (as indicated above), quite likely due to the range of methanol generated in the various traditional production processes. Spirits from a selected list of fruit species have an allowable methanol content that is higher than the general limit for fruit spirits, for example (see European Parliament and of the Council (EU). 2019/787 Definition, description, presentation and labelling of spirit drinks, the use of the names of spirit drinks in the presentation and labelling of other foodstuff. Off. J. Eur. Union 2019, L 130, 1–54) Conversely, other countries, such as US and Australia have a flat limit for all spirits, which is higher than the EU limit for wine spirit and brandy, but lower than the EU limit for fruit spirits. So in these countries it appears to be more a simple balance of safety vs process probably with less consideration for adulteration.
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Freshwater Mussels are important and in trouble
I do not have any expertise in that field, and my knowledge if pretty much limited to talks I heard from colleagues who are work in fields related to invasive species. But from my limited understanding there are various definitions for invasive species, which can vary in use, depending on context (e.g. depending on ecosystem, whether it is a research vs policy vs conservation, etc.). Roughly speaking, in policy terms certain non-native species can be categorized if their introduction has potential to cause economic, environmental or human health harm. Factors can be highly artificial, as for example certain form of agriculture, animal husbandry etc. can be highly sensitive to even somewhat moderate influences, which might not be a factor in a pristine ecosystem. There are a few studies that show reduced biodiversity in forest sites. Not sure about the effect size, though. Another issue with these evaluations is that for risk assessments a variety of factors might be used, e.g. growth rate, behaviour in other habitats, similarity of ecologic niches compared to native species, and so on. IOW, it is difficult to be certain of the damages until at least some damages has been done, at which point it might be too late. To complicate matters, literature often discusses invasiveness outside of these policy definitions, for example if a non-native species spreads into a new habitat, regardless of short or long-term damages to the system (which can be difficult to assess for a wide range of reasons). So what I took home from the these talks is mostly that a) it is important to check carefully the context in which invasive species are discussed b) that often (but not always) proactive strategies are good a idea as in some cases the impact on biodiversity can be rather massive, but c) data is often sparse and there is almost always at least some (necessary) level of extrapolation going on.
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New Zealand Smoking Law
From the looks of it, the measures are a fair bit different. I have not read up much on it, but it seems mostly restrict supply, but does not seem to e.g. criminalize private consumption. It is obviously early to tell what the effects are going to be, but considering that the smoking rates have dropped quite a bit in NZ already, there is a decent chance that the smoking rates will decline further just by making it more difficult to get to them.
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Boiling chestnuts...
Generally speaking a larger volume allows more constant temperature and less temperature drop when you add ingredients. Also it results in less crowding, less surface effects and related geometric issues.
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How to be motivated to do a work that you really want to accomplish ?
That part really seems like procrastination to me. Essentially it is the tendency of folks to seek out activities that makes them feel better right now and putting off tasks that could make them feel bad. This is especially problematic for long-term projects, as the expected reward is only to be found at the end, whereas playing a game will make you feel better right now. There are few ways to handle these kind of things, which can include changing you mindset. But simpler method, e.g. rewarding yourself by setting yourself certain rules can also help, too. For example, you could say set yourself a rule that only after working for a certain amount of time, you get to reward yourself (say take break, have a treat but something that does not distract you too much). Set yourself milestone for the day and if you get to the point you allow yourself to do something you like for a set amount of time.
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'The Talented Mr Ripley'
I would assume that the main issue here is the financing source. Everything else seems to be fairly accepted practice at this point.
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Swimming with crocodiles - How is that even possible?
Generally speaking, it is not safe to be in close proximity to any predator. Crocodiles are mostly opportunistic hunters and can go for long stretches before feeding. Unless folks have fed them or have observed them feeding I would guess that there is no easy way to predict potential attack pattern. I also doubt that scientists would get into close contact with them without security measures. Jumping into the water with them would not be studying them, it would at minimum interfere with them.
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On the lab leak theory
Indeed. Basically any folks with extended contact with animals are at risk of zoonotic spillover. One very common zoonotic disease is toxoplasmosis. Around 11% of the population 6 years and older have it in the US. In Irish farmers that level is around 70%. Farmers are also exposed to many other zoonotic infections with high frequencies including Coxiella burnetii, Borrelia burgdorferi or Leptospira interrogans. Also with regards to gain of function research, the term is not that well defined, and in the broadest sense could include any genetic manipulation of pathogens (animal or human). In that sense almost all microbial and virological lab, including the one in Wuhan would fall under it. In the strictest sense, which is under more scrutiny is to do specific manipulations which are expected to allow or enhance pathogenic interactions with humans. That type of research was not part of the research done in that lab (according to NIH reports, that is).
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Frozen nose hair: what are your extreme cold experiences?
If I remember correctly the issue is that cotton actually does retain water rather well. Once wet, they do not provide thermal insulation. In contrast, contrast, wool can wick moisture due to capillary actions fairly well. Also, hydrophobic materials do actually work well as undergarments- a lot of thermal underwear is made with synthetic and synthetic mixes. I think one of the things we were told was to slowly warm up persons, starting with the core (not the extremities, due to the reasons you mentioned).
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Frozen nose hair: what are your extreme cold experiences?
You are not my boss, you cannot tell me what to do! I think most good ways to maintain temperature are actually the obvious ones (wear layers, cover exposed skin, shelter from wind, etc.). Many others things offer temporary relief, but once we are past the -20C (and wind chill!) things get rather complicated (or easy, depending on perspective).
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What would be the most important thing than humans should try to achieve in priority in your opinion ?
In addition, carbon production is a decent indicator of resource use, which in turn in related to things like habitat loss. Moreover, often habitats are not destroyed to fulfil the immediate needs of the local population, but in order to produce goods and food items for rich countries. The average US-American consumes 20 times the amount of meat as the average Ethiopian. So following this logic The most effective way is to abolish lifestyle and reduce populations of affluent nations first.
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What would be the most important thing than humans should try to achieve in priority in your opinion ?
Often these arguments are just a poor excuse not to do anything. E.g. the thought that any reduction of emissions is meaningless, as China is producing so much. Often sprinkled with bigoted sentiments (we are not the problem, those folks are). Thereby we are repeatedly shooting ourselves in the foot in an effort to sit an on an issue up until we are forced to do something. Seems to the modus operandi for a lot of population-wide issues, including the pandemic, for example.
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Frozen nose hair: what are your extreme cold experiences?
Missing a bus and waiting for ~30 mins at around -35 C was fairly unpleasant.
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Aliens and FBI
That does not work. DNA/RNA does not provide information on the cellular environment as such. I.e. you cannot use genetic information to create cells. You will have to start with whole cells to begin with (if we want to ignore some sci-fi element that makes it magically possible that is).
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What would be the most important thing than humans should try to achieve in priority in your opinion ?
A few things here: as TheVat mentioned, birth control is not the sole issue, improving standard of living is one of the drivers of reduced birth rates. Also, the number of people will continue to increase due to demographic momentum. The only way to reduce the number of folks is to actually kill people off. And also the focus on population alone is very misleading. Countries that have positive population growth tend to use much fewer resources than their counterparts with declining or stabilizing populations. Each Canadian has the CO2 footprint of about 200 Somalians, for example. Sorry to hear that it happened to you, too. Now talking to folks from way back, these types of gaslighting were shockingly common. There is a bit of a momentum in various health system to combat that, but despite improvements, there are still rather horrific cases out there.
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What would be the most important thing than humans should try to achieve in priority in your opinion ?
I think this looks like extra privilege as it lacks the added context why it is important to show being inclusive. The issue is that studies have shown that in many countries the health system underservices minority patients. Especially, but not limited to indigenous persons. These issues also overlap with socio-economic factors so by paying that extra care the hope is to raise the level of health outcomes to at least something approaching that of majority patients. If we are talking about anecdotes, I have somethin to share specifically in that area. When my father fell ill and was extreme pain he was diagnosed with home sickness and the MD told him that he just wants to get back to his home country. While he narrowly avoided losing the use of his legs, and he managed to continue working until retirement, he is in constant pain. The disease itself is easily diagnosed if just the same level of care had been given as to a majority patient. Also, it was not just one MD. After the first made his ridiculous diagnosis it was impossible to get a dissenting second opinion. Now, this was quite a long time ago, but these attitudes were extremely prevalent. So the course correction you mentioned there is not extra privilege. It is a countermeasure to be being treated extra-shitty.
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Aliens and FBI
There is even more to it. You need basically a kind of cellular environment for it to its proper thing. You can (to some extent) throw together RNA, ribosomes, enzymes, amino acids and the proper buffer together to produce proteins, but those would not do much. They need other proteins, all kind of metabolites membranes etc. to sustain function. So it is exactly right that we actually need functional cells to actually do something.
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The things that intrigue me most about the human body.
Exactly.