Genetics

Hi again, A very simple statement I would like to test. "In a normal adult person, the only somatic cell mutation (happening for instance during DNA replication) whose expression could be appreciated by other humans is Cancer" Many thanks.

I hope no offence is taken here, and none is meant. However I am using as my definition the following: Nerd - A person who is single-minded or accomplished in scientific or technical pursuits but is felt to be socially inept. http://www.thefreedictionary.com/nerd I just wondered how much of 'nerdy' behaviour is actually inherited and how much can be attributed to the environment? Moreover, is it causing a social distancing from more aggressive, selfish and downright nasty people which are to be found in most workplaces? (Incidentally , I grew up initially as a streetwise Glasgow boy into a man interested in everything but master of nothing).

I'm just learning mitosis for the first time so bare with me here. I understand that during interphase the chromosomes are difficult to see. Also they duplicate during S-phase. 1)Are they chromatin at this point or still chromosomes? 2)How are the male and female traits divided at this point? If they are chromatin how are they divided? If they are chromosomes how are they divided?

X-inactivation (http://en.wikipedia.org/wiki/X_inactivation) is a process where a gene inactivates one of the two copies of the X chromosome (chosen by random in each cell) (however some genes could remain activated) A) Is anybody using this to inactivate chromosomes as a kind of gene therapy? B) Taking the case of Haemophilia (http://en.wikipedia.org/wiki/Haemophilia). You need to have two Xs chromosomes with the disorder to express the disease. But if we are inactivating one of the Xs by random in each cell (imagine 50% of the cells have the good X copy inactivated), shouldn't women carrier of the disease at least express some symp…

According to wikipedia, The 3 billion base pairs of the haploid human genome correspond to an information content of about 750 megabytes. The entropy rate of the genome differs significantly between coding and non-coding sequences. It is close to the maximum of 2 bits per base pair for the coding sequenes (about 45 million base pairs), and between 1.5 and 1.9 bits per base pair for each individual chromosome, except for the Y chromosome, which has an entropy rate below 0.9 bits per base pair. In other words, we could store a copy of our genome on a CD. Despite having put this in the genetics forum, what I'm interested in is how much information is contained …

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When I did the shotgun sequencing. The DNA fragments were sheared into 400~500bp then ligased into plasmid vector. These ligation were transformed into competent E.coli, followed by colony screening and 2nd enrichment of selected colony in 96 well plate. The results come out that there is only one sequence (insertion) result from one individual well. Although I knew the E. coli in each individual well was replicated from a single colony I picked up, I am wondering why won't be more than one insertions existed in a single E. coli? Is it possible that different insertions were uptaken into the same competent cell in the earlier step? Thanks!

Hi! My name is Emily, and I am a high school senior in my Aquatic Biology/Scientific Research Honors class. For our final project, we have to write a scientific paper on anything to do with aquatic habitats. (water, fish, streams, etc.) I am very interested in Genetics, so I was hoping to do my research on something to do with it. My teacher is allowing me access to her RNA Extraction equipment. However, she has never had a successful extraction. I would really like to maybe compare RNA of 2 different organisms from the same species. The Questions: 1. Is there a specific aquatic organism's RNA that would be the best/easiest to extract? 2. How should a high school…

Does anyone in the scientific communinity believe the viruses precede the funtion of life and or cells. Like before there is life there is a virus that predates the function of the gene or even a computer for that matter or does science believe that life predates the virus. Is there anyway in knowing can scientist study the genes of ancent viruses. And does anyone knoe what the results are

I know in some clinics now they let you choose the gender of the baby and even eye color. they do this through implantation genetic diagnosis. As i understand this chooses the embryo with the characteristics that you want and those are the ones that get implanted. I was wondering, does this means the baby can just have the same eye color of any of the parents? What happens if you want the baby to have the same eye color of one of the grandmothers..will this be possible? Also what happens if you want the baby to have an eye color that doesn't run in any of the parents families..can this be achieved? will you need an extra person with those eye characteristics and…

Does anybody knows programs or the Internet resources for interpretation of the data of genetic testing (polymorphisms) for humans? I found only http://www.warfarindosing.org/ Thanks

I have just seen Waterboy with Adam Sandler for the umpteenth time especially the famous scene with the Col. Sanders lookalike professor where the Waterboy is ridiculed for references to his Mama's sayings. Then I read this and wondered if he wasn't correct all along: Can Happiness Be Inherited? http://www.sciencedaily.com/releases/2009/05/090514101937.htm So, apart from the mechanical forces on the cells changing gene expressions (tensegrity) happiness also passes on genetically from Mama to you... how many people believe this?

Does his skin condition affect that too. I was just wondering and wanted a scientific perspective.

what gene causes porphyria? google isn't helping, and i need to know what chromosome causes the disease. there's different kinds of porphyria, and more than one are genetic, so there may be more than one chromosome. thx in advance.

Ok, I know nothing about genetics! Me my Dad and my daughter have an identically shaped toe nail which is obviously inherited, i.e. same shape same toe. By looking at out genes is it possible to figure out which gene causes this? Is this of value? if there was a register of such things surely it would enable researchers to figure out which genes did what and therefore highlight which ones were more important for medical research! Does a register exist? As I said "I know nothing!!!!"

Hi, I was wondering if somebody could help me with drawing of genes. I'm looking for a software/program/scrip/anything that would nicely present a gene with its exons, non-coding regions and SNPs (preferably be able to present different group of SNPs in different colors). Your help will be greatly appreciated! Many thanks!

When I was younger I new how to get mad untill my veins bulged and wife took off into another room. As now i'm at 67 years old I relized to wonder ( I've lost it ) my ability to get mad of depression and anger. What happened to me ?. I love to joke around and laugh more. Did I reach old age ?. I still have a full set of hair and perfect teeth and go to Balleys gym regularly have sex with my wife at lest twice a week and still tel her that she looks very pretty in the morning and she tells me she knows what I want. I told her that L'm not dead yet. I love to travel the world with her and I been retired for 6 years from farmingAlmonds. Is my body feeling…

How do you go about cloning.?

http://www.sciencedaily.com/releases/2009/06/090605123237.htm "ScienceDaily (June 8, 2009) — Boys who carry a particular variation of the gene Monoamine oxidase A (MAOA), sometimes called the "warrior gene," are more likely not only to join gangs but also to be among the most violent members and to use weapons, according to a new study from The Florida State University that is the first to confirm an MAOA link specifically to gangs and guns."

Hi all, I have some dumb questions about insertions/deletions A) What is more common (regarding the changes in the genome), insertions or deletions? B) What is more common (insertions or deletions) regarding the genome area (introns vs exons)? C) If insertions are more common, then the genomes are in a continuous expansion (that in the end means more junk DNA nature has to play with). Is there any lab method (I mean physical method) to measure the potential length of the genome of an organism before sequencing? (no idea, maybe weighting the chromosomes?)

I found this article at national geographic discussing the possiblities of cloning mammoths. I always thought that it was near impossible to clone something that has been dead for so long due to the breakdown of vital cloning components. Not to mention the funding needed to clone a mammoth which would be phenomenal. Anyone think it's a possiblity or have any thoughts? National Geographic Article Click here

I don't understand the meaning of "enrich" in the sense of a gene being enriched in a chromosomal region and I've failed to find a definition thus far. Thank you in advance for your answers!

Ever find Billowy Spider webs travel high in the wind ?. The fall time is the right time to see them webs wraped on Hellicopter rotors and parking lot lamp posts and your radio antenna. A true story on evolution in the spiders nature. My daughter and I went shopping to K-Mart one evening in the fall. We parked our car and my dauther noticed webbing on every lamp post. Then I had a thought in my brain and my answer was that when they migrate on long billowy webs that three days after we will get our first heavy rain. Well we did get our down pour two days after a dry summer. Also I told her that in nature when they raise up thier abdomen purched hi…

I'm wondering if anyone could help me with a genetics problem. I know that for RNA Polymerase II genes - you have a promoter, on which forms the preinitiation complex (PIC). As part of this apparatus, you have general transcription factors (GTFs) necessary for basal transcription in vitro. Things like TFIID, TFIIB, etc. But for efficient transcription in vivo, you need activators and co-activators, yeah? Activators bind to enhancers way upstream (or downstream!), which then bind to co-activators which can either (i) associate with the PIC directly, like certain TAFs and mediator OR (ii) remodel the chromatin to make things slide along easily. What I've just de…

I saw that they managed to splice a tobacco plant with firefly genes and made a glow in the dark tobacco plant. Genetics is obviously advanced enough to do all sorts of mad modifications to plant genomes. Is it beyond the realm of possibility that introducing say oak tree genes to the cannabis plant genome may result in a cannabis tree?