Organic Chemistry

Hi all, I am conducting research into photo-protection of human skin to prevent skin damage. I have received a promising small molecule compound from a Chinese supplier and I have conducted some basic tests to check if it is in fact the correct substance. So far, I have received a HPLC analysis and also an independent mass spec, which seems to match the target compound (see below). Do you think is it also necessary to have a NMR analysis to confirm the structure? In other words, is it possible that the compound I have received could be 'structurally incorrect', despite having the same mass as the target compound? Any help or comments to answer this question…

Hello, so I’m making a sour dough starter and I’m trying to figure out how it works. Does anyone know if alpha amylase produces high amounts of co2 gas when converting amylose to maltose and other sugars?

Hi all, in our lab, tris salt reagent has an expiration date (2012) but my boss told me that this kind of salt does not expires. anyone knows if tris(hydroxymethyl)aminomethane expires ? Kind regards.

Hi everyone, do somebody know how hexamethylenetetramine react with isocyanate? Thanks for your answer

I am looking for an easily readable synthesis on Tramadol HCL. Can someone give me a step by step manual and a simplified version of any of the currently existing syntheses? -Please.

Hello friends I dont understand how the end product is the answer. I have labeled the partial charges. Did I do them wrong? My reasoning is that the ph are EDG. thank you in advance

I made Chloromethane from mixing methanol with HCl, and I was wondering that is it possible to replace the hydrogen atom with nitrate substance/ion? Thank you

Does aluminium oxide and carboxylic acid mix to create a water resistant/repellent substance/liquid? Or is that wrong?

How to prepare 0.23 N HNO3 solution in 12.3 ml volume

Hello guys! I am studying A-Level chemistry in Grade 12. Regarding the Carbon-13 NMR spectrum of Phenol, I do not seem to understand why we get 4 distinct peaks. Can someone be so kind as to explain why carbons 2 and 6, and carbons 3,4,5 have different peaks?

There are two ester groups so I think it's a Dieckmann condensation, but that CN is making me nervous. I think the esters make the alpha more acidic than the CN does that is why I deprotinated the H by the ester. Any help is appreciated thanks

Does water have calories? My friend thinks so because joules can be converted to calories and water has energy (joules). I disagree because saying such is akin to saying "a line has meters" rather than "a line has length" which is improper, therefore so is "water has calories." Who is right here, and why?

i am a student in Computer science and i don't know alot in chemistry but i want to make the silver conductive ink , the know that used in the pens to conduct electricity , i want to make the experiment 1 time only , just to use it in my final graduation project . i found the formula on the youtube : The ink is created by placing an aqueous solution of silver nitrate into a flask of water combined with polyacrylic acid (PAA) and diethanolamine (DEA), the capping agent and reducing agent, respectively. After about twenty hours, the silver nitrate is dissolved, forming particles with a diameter of about 5 nanometers. In order to enlarge the size of the partic…

Hello, I don't understand where the H3O+ comes into play, so I could have missed the mark by using the base as acid base chem instead of using it as a acyl transfer.

better late than never? Why does the OH leave in the 4th step? why does this need to happen? thanks in advance

Would someone be able to explain how the light-sensitive organic molecule methylene blue breaks down under photonic illumination? I often see reports of oxidisation, but this is a reversible process and not an outright breaking of the methylene blue molecule. I know that the 664nm absorption resonance is due to a transition from the nonbonding state to the antibonding state. Does the antibonding state weaken the bond so much so that the molecule is broken more easily somehow? Many thanks in advance!

Hello everyone, I think this could be a pretty long post, just so you know. I'm a Master's student Bio-Engineering, and for my thesis I have to synthesize '15-crown-5 ' crown ether. I have been trying to do this in the laboratory for the past 4 months, without any decent yields. I am following an older protocol of Smid et al. 'Substituent Effects on the stability of cation complexes of 4'-substituted monobenzo crown ethers'. It is the image without the yellow text. I added the protocol here. It's been quite a disaster really. After numerous tries I've only managed to synthesize about 2 grams... As my background is more environmental sciences and not o…

I recently completed a lab dealing with electrophilic bromination and nitration of phenacetin. The bromination product revealed a bromine group ortho to the ethoxy substituent, while the nitration product revealed a nitro group ortho to the acetamide group. I know both the alkoxy and acetamide group are ortho-para directors, so why do the nitro and bromo groups substitute at different positions on the aromatic ring? Is this a result of steric effects or something different?

This was my attempt in a Balz-Schiemann reaction. In a three neck round bottom flask containing HCl i added a thermometer, a dropping funnel and a powder funnel. The flask was cooled in an ice bath. I slowly added some amount of m-phenylenediamine through the powder funnel. Then, I added drop-wise some aqueous sodium nitrite solution through the dropping funnel. I was careful not to add the reagents too fast. The temperature did not exceed 7 Celsius. The problem that occurred was that the reaction started to produce massive amounts of foam. The flask overflowed. I tried to make room for the gas to come out but it did not work. I decided to transfer the solution …

1.How would you approach to predict an a) inorganic chemical reaction b) Organic chemical reaction B. Are structural and electronic configuration enough to understand a compounds behaviour and properties. (Assuming temperature and pressure can be varied freely) C. What are the basic concept that a person have to master in order to be an expert in Organic chemistry.

On the attached file I have tried to work out the reaction pathway. The reaction given at the top is from a chemistry lecture I watched but no mechanism was given. In the first mechanism I just reacted one of the N20 molecules with hydroxide. The hydroxide attaching to the Nitrogen and is then deprotenated by the second OH- I now have H20 and N03- but it doesn't explain how the second N20 molecule ends up with a second electron on the Nitrogen. In the second mechanism (which I think is correct) the 2 N20 molecules join together to form the dimer N2O4. OH- attacks the anti bonding orbital of the Positive Nitrogen and the 2 electrons from the N-N bond go onto t…

I'm a midwife trying to make sense out of an evidence based article. We only use gram per liter in fibrinogen, who can help me?

Dear Scientific community I have dehydrated (almost 100%) isopropyl alcohol. This alcohol has a strong bad scent and I want to use this isopropyl alcohol as a base (raw material ) in a windshield washer fluid. BUT because of this strong smell I can not. Is there a technique or a machine that can take out the smell from dehydrated isopropyl alcohol before I can mix it to make the washer ? PS adding industrial grade scents to kill the original smell does not work. Thank you !

Question: which OH is more likely to attack the aldehyde? I think it would be the one the tertiary C because the Positive charge that is created of the O will be stabilized through hyper conjugation.

The strong CH3 Nuc would deprotinate the OH rather than react with the ketone? If so is there a lewis acid source to protinate the O? Could I also get a hint on how the strong C [excess] would impact the compound?