Genetics

Hi, i'm wondering if this is correct for primers and sequencing etc. its just what i've gathered from trying to understand it.. So is it that DNA strands will respond to the primer of another if its compatible, whereby the complementary base pairs are pieced together since recognition is apparent in both strands.. kind of like piecing a jigsaw together whereby even if there are missing pieces, in general the details will be able to be placed in or connected because they are unique to their localities of the puzzle..., therefore in DNA, the nucleotides are specific to their strands and can therefore replace missing links for a complete sequence, even if they are…

I find the George Price made a great contribution to Genetics and got very little credit or appeal for his work. His ideas and formulas were brilliant and he interests me greatly, he was about to write a book called "No Easy Way" but it never got published. Anyone else that would like to share interest on George Price or any other profound Genius or have any information on where one might find this unfinished manuscript or articles he wrote, your posts would be accepted happily.

Hello There are not many studies which use SNPs for contemporary dispersal estimates. From the journal articles I cannot really figure out why. Does anybody know why SNP's would not be useful in a study of contemporary migration between meta populations? Thanks

Is it possibile to find the meaning of all ATGC combinations in DNA? If yes what will be the consequences?

If 2 people who have Down's Syndrome have a child , what is the chance of that child having Down's Syndrome ?

Hello there for the first time dear scienceforums users I have a question to ask you that has been bothering me for quite some time. I have natural predominant brown hair color, but sometimes my mother says she finds blond hairs and even red hairs on my head. Is that possible? Can someone have different natural hair colors? Cheers

Hello; i am new to the forum. I would like to ask you about selective breeding and the chances of producing a Taurus (bull) that displayed favourable traits and phenotypes of 2 selectively-picked cattle; thus to produce a better offspring as a result. Taurus have 30 chromosome pairs; so what are the potential outcomes of the breeding? How do favourable phenotypes become dominant? is that just a result of the phenotype being heterozygous dominant? Am i correct in thinking that it is important to keep as many different phenotype combinations in genes as possible; as this allows for diversity within a species?!? if the potential phenotypic combinations were r…

I'm a computer science student doing my software project on chromosomes. I need microscopic images of chromosomes without overlaps and crossovers with clear band pattern. The image i posted has some overlaps and crossovers when i count the number of images the overlapped chromosomes are counted as one. My research concept is based on classification so I need a well good spread image to classify the chromosomes. Please suggest me the link or suggest your ideas where I can find the images. If possible mail me the link. I'm badly in need of it.

Having just completed my BSc majoring in genetics and starting postgrad study next year, I am interested in finding books related to genetics - specifically human medical genetics but a more general overview of current genetics research is also fine. Preferably something above the level of a layman but not so technically advanced that only somone with a PhD related to the topic could understand it. It has to be current and well-written. Cheers.

In humans, the ability to taste PTC is dominant over non-tasting. Two heterozygous tasters have three children. What is the probability that one or more of the children will be non-tasters? a. 0.684 b. 0.578 c. 0.251 d. 0.422 e. 0.004 I assumed that the two heterozygous parents would have a 1/4 chance of passing on the recessive, non-tasting gene, aa. With three children, I would think to use the product rule, thus multiplying (1/4)(1/4)(1/4)= 1/64 = 0.0156 Please help explain what I have done wrong. Thank you.

here i am giving two types of solutions.plz tell me which is correct and why! A randomly mating population of your favourite diploid animal has the dominant allele |B| and the recessive allele "b" at the frequencies 0.65 and 0.35. A sudden cataclysmic event causes all of the homozygous recessive individuals to die. You are very sad but take comfort in the fact that your favourite animals are resilient creatures that simply carry on with life and get busy mating. What was the percentage of homozygous recessive individuals before the cataclysm, and what is the percentage of homozygous recessive individuals born in the first generation conceived after the cataclysm?…

I am studying genetics in school right now, and my teacher told me that dwarfism is actually a dominant trait, but since people with dwarfism didn't survive in the early ages, the trait is not present in the gene pool. so i looked it up... Achondroplasia, the gene disorder associated with dwarfism is an autosomal dominant genetic disorder. Now I got to thinking... If people with dwarfism who are achondroplastic survive much more often today than they had in the early days, will the dominant trait start to take over? ...after maybe ten thousand years of civilization? Dwarves will take over the world... O.o

Hello On a Gel electrophoresis why do the bands come out in one set of places if you use restriction enzymes seprately and then in in different places if you combine them? And in different numbers? For example EcoR I and Hind III. EcoR I has two restriction sites. Hind III has three restriction sites. Should not the two combined have five restriction sites? My gel only has three sites. And why are they in different places than the single lains in the gel? Thankyou

What are some movies related to cytogenetics? I know only two -- The Boy in the Plastic Bubble starring John Travolta, and Gattaca. Please help.

Hi Does anyone know why finding restriction site loci and sizes is useful? and also why finding the sequence of an intron is useful? Or any good sites that detail why. Thank you!

Dear all, I`m working on gene overexpression using adenovirus. It`s the first time for me and I have question on how can we differentiate recombinant ad plasmid with pshuttle vector ( before recombination with competent cells) through gel electrophoresis? Thank you very much. Inersia_uteri

mTOR signaling tells Cyclin E we are about to replicate DNA but there are no Amino Acids. If mTOR signals are not present and you replicate DNA.....apoptosis will occur.. Why is this the case? and is TGF-B signaling needed and why?

Ok, here goes, Hi, as you can probably see my name's Dec, I'm 13, and this is my first post, now, to the question. I'm currently in the process or writing a novel, and even though I'm quite gifted in terms of intelligence, I needed a bit more than common sense and, lets say, maybe a GCSE level understanding of science (No modesty here.) to answer this question. In my novel, two different species were originally descended from a common ancestor, but not in a slow-process such as evolution, now one individual of each species at some point in the distant future, come together and reproduce, and "create" my main character, my question is, is this possible, because if…

Good day, I would just like to ask for suggestions in my thesis topic: Cytochrome p450 2e1 mutation in female smokers and nonsmokers ages 18-65 years old All i know about this topic is that: "Cytochrome P450 E1 or CPY2E1 is one of the enzymes that are critically important; they are involved in oxidizing carcinogens which are found in tobacco and is probably associated with nasopharyngeal carcinoma or cancer originating in the nasopharynx." Since I'm not really familiar with the basics of genetics. I would just like to ask your thoughts/ suggestions on what are the possible thesis statements and methodology (and if possible, the easy ones to do related with cyp2…

I am still trying to wrap my brain around DNA. It looks like the DNA strands contribute to the protein synthesis process. But how can we go to DNA synthesis to proteins to...a person's eye color being a certain color. Maybe it is the protein synthesis part that I am missing? Do the proteins created for the cell give the cell certain properties such that the cells making up the eye will have the color? Another question, do scientists know that this particular sequence of DNA contributes to protein generation for these particular cells. For example, is such that: DNA Sequence 1,2,3 contributes to eye color, etc? Is it that simple?

In one genetics book, the definition of polymorphism is listed as 'the existence of two or more discontinuous, segregating phenotypes in a population'. what exactly do 'discontinuous' and 'segregating' mean in this context? I understand the basic definition of polymorphism as the presence of 2+ alleles in a population that gives rise to 2+ phenotypes.

what is gene therapy? how does it serves to work for cancers?

Despite many great scientific minds having undertaken cousin marriages in the past, notably Charles Darwin and Albert Einstein, there appears to be this skeptism within our modern western society that it is somehow 'icky' and wrong. Where do these ideas come from and are these feelings justified or are they just irrational? I am also aware of that there have been studies on this and that it has been determined that cousin marriages result in an increase in the likelihood of birth defects in offspring compared to those of regular marriages involving more unrelated individuals. However, what are the exact statistics? Is it recommended that humans mate with those they ar…

Hi! What is a deficiency screen? I know it is used to determine potential regulators of a gene... but I don't understand the mechanism! Can someone please explain??? And, Why do you have to "sensitize" the sample first??? Thanks a bunch!!!

Hello, My profession is not genetic, but I have a general knowledge on development of races and human evolution, so please forgive me if I write a wrong notation. According to the evolution theory, humanbeing was in same genetic family as all the ape kinds, we were one of the ape kinds with a primitive brain. Then for a reason, humanbeing developed his learning ability, developed shelters (like cave houses), hunting technics, cooking, discovered fire, new transportation technics, built up new human relationships, culture and civilizations. Finally we became superlative creatures in the planet. My question is "how" or "why" humanbeing developed his learning abi…