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Genetics

DNA replication, Mendelian Genetics, mechanisms of gene expression, and related topics

  1. Started by b3n3llis,

    With 23 pairs of chromosomes in a human, how is each pair named and differentiated, if at all? There's Chromosome 1, 2, 3, 4, etc but how is it each pair differentiated, eg. 1a, 1b or 1p, 1m (parental/maternal) or 1xx, 1xy? One pair of shoes are differentiated by 'left' and 'right', whatabout chromosomes? If they're not, why not? Many thanks.

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  2. Hi there, I am new to the forum. I came searching for information about Genetic testing. I am new to this whole topic. Please help. I am 24 years old. A guy proposed to marry me. The thing is, he is my second cousin. I heard/read about the discouragement for cousin marriages by some experts. I am kindda worried, and until this day, I did not accept or decline the guy's proposal. I don't know what to do. What I know is that I want to do the right thing which will benefit everyone (specifically speaking, the offspring). My parents are first cousins. I have 2 sisters who don't have the best mental health condition; without going into lots of details about my sisters…

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  3. Hello, There is a lot of discussion with difference groups of people having higher/lower IQ based on genetics. Are there accredited scientists who share this view or is it relegated to the fringe? I can find the scientists who support this view as well as those that are against it but I don't know the best way to find out what is considered the fringe view versus the mainstream or at least well supported view. Thanks. Regards, Chris K.

  4. Started by Mystery_of_GodST,

    Is it possibile for forensic scientists to identify an individuals identity whether it be through hair, saliva, blood, semen, skin, sweat, mucus or sarwax? I know this is the standard of linking suspects to a crime scene, but could someone tell me how does it work if it's possibile? I can't comprehend how it could be done because I can't figure out where you would start from in order to match and identify it.

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  5. Hello Super Geniuses (and I mean that in the highest regard), I need some really big help. I have recently been hired to pen the script for a new action/thriller motion picture, based off a very loose treatment. I am in deperate need of help as the central crux is about a drug that allows RNA to communicate with DNA in a way to cure most, if not all, disease, ailments etc etc. Please, if this is prepostuous, try not to demoralize my retardation. I am merely a writer. I have been doing some research online and to be honest, it might as well be written in ancient Greek with heiroglyphics as the footnotes. I am trying to in as simple as terms as possible, underst…

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  6. Started by tradur,

    I'm trying to find out info on a pdha1 mutation located at intron 8 . I don't understand the genetics test and want to research it in detail. I was hoping a smart student or gentecis savy formum member could clue me in a bit. IVS8 31+15C>T was the finding when sequencing pdha1 gene. This relates to a baby who has an undiagnosed disorder(suspected mitochondial). It's the only genetic abnormality we've been able to find and virually the only clue we have for him. The doctors consider it a variant likely non pathogenic, but I am not so sure. His symptoms match perfectly for pdha1 mutation typical of pdhc deficiency. My goal is to try to find out more details o…

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  7. Started by 1123581321,

    I was wondering if the difference between mitosis and meiosis is where meiosis creates haploid gametes constantly from other cells by changing them into haploid for that gender and mitosis is really just the addition of the other set of sex chromosomes and dividing them into what we have...

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  8. Started by Mutad0r,

    First off, I'd like to say that the cat is dead. She died about 5 years ago. So anyway, we had a cat. She was left at the door of the church in the winter, so we do not know where she came from. She had a particularly interesting perk ( although sadly, I only now realize how important of a discovery it COULD have been.). Of about 7 times that she had kittens, all of them were female. She always had 3 kittens at a time, so that would make 21 females in total, 2 of which we kept, neither seemed to have the perk. I also understand that it could have been a lucky streak, but I was wondering what could cause only female kittens and how much of an impact this could have …

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  9. Started by SCIFI01,

    I love my science but I was never good at mathematics and I can't figure this one out. I had a parental DNA test done with testing samples from my child, myself and her mother. The test came back saying there was 99.9% probability I was the biological father. They also said that I am 16,997 times more likely to produce a child with the required alleles than a random dude. 10 different Locus sites were tested and the alleles are below. (The first two numbers on each line below represent the mothers alleles, the third and fourth represent my child and the fifth and sixth represent my alleles). MUM CHILD DAD 5,6 - 5,5 - 5,5 * 3…

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  10. Started by ksue12,

    I'm curious, and if I word this wrong, please forgive my misunderstanding! If someone has a problem with one part of the SLC family, does that predispose them to a higher likelihood of having a problem with other parts of the SLC family? Say, if you are found to have an issue with SLC6A2, is it likely that you might have an issue with SLC26A2, or even a couple others? I've been reading and rereading on all this, and I couldn't find anything that explains if it is likely or not.

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  11. Started by Vindhya,

    If a mother is hemophilic-A and father is hemophilic-B then what type of hemophilia the daughter may suffer from ?

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  12. Started by 1123581321,

    I was wondering which way RNA is fed through in protein synthesis... is it from the 5' too the 3' or the other way and what is the RNA strand called which is synthesised in the nucleus before being carried to the ribosome..

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  13. Started by D^3,

    The basic equation for LD (linkage disequilibrium), for those who might not know, is: D = P(AB) - P(A)P(B); D = LD and P(n) = frequency of "n" every equation I've come across requires one to know P(AB) before finding D. Is there a method to solving for D without knowledge of P(AB)?

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  14. In Golden rice three genetic traits are recombinant in its dna: Phytoene synthase (psy), phytoene desaturase (crt1) and lycopene cyclase (lyc). I cannot find where lycopene cyclase is derived from which organism (in this case golden rice)

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  15. Started by Aleksander,

    I have light brown eyes - I want to know what were my chances to have blue or green eyes in % - In my father side there's virtually nobody with dark eyes. - In my mother side there are 2 cases - her uncle (mother side) and grandfather (father side) - I put up a detailed list. and I have 4 additional question .. Sorry for having so many questions ..but it's very difficult to find answers on the web..especially when it's in more details 1.) If my mother have a brother with blue eyes and a sister with light green eyes - is she automatically a carrier of the recessive gene for light eyes ?? or there are chances she could not ? 2.) If my father has blue eyes …

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  16. Started by npbreakthrough,

    if binary is to 2, then genetic is to ?? basically , if you boil down to the most basic building blocks of the genetic code.....how many are unique?

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  17. Started by readytogo,

    Hi, I am hoping someone can help me - I want to check if there is LD across a gene locus I am studying. I have accessed the HapMap LD data and managed to download it to give me D', r2 and LOD values between the SNPs within the region of interest. How do you interpret this? I mean - how can I use this info to make judgement on whether there is LD across this region (approximately 200kb region). What do I do with the data? Please help! I have posted on here before and not had a single reply - I would really really appreciate it. Thank you

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  18. Started by Peron,

    I'm just wondering if a hermaphrodite, with functioning testicles and ovaries, impregnate herself and give birth. Is it anyway possible? Should she just being cloning herself?

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  19. According to the examples in this webpage ( http://en.wikipedia.org/wiki/Tajima’s_D ), it seems that pairwise difference between any two sequence pair never exceeds the number of segregating sites. How could their difference lead to a positive d, which results in positive tajima D? The example can look like this: >sequence1: TTTTT >sequence2: ATTGT >sequence3: ATTGT segregating sites: 2 average pairwise difference: (2+2+0)/3=4/3 Thanks a lot!

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  20. Started by pippo,

    People, Wondering what your advice would be on this- say you have a tomato plant, and snip off a tip of it (5-6"), and add rooting hormone, plant carefully, and wait until it grows/takes on roots pretty well. Of course, it should produce the same tomatoes, one would assume. But say you repeat this again, say, when the new plant reaches a good height of about 2-3', and starts to wither again, at which time you snip off , again, another 5-6" of plant tip to start growth again. Of course, you again, would expect tomato fruit. Can this continue forever? I heard this can lead to genetic bottlenecking (which I think means concentration of defective genes.........) I ca…

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  21. Started by Larix,

    I ask the reader to evaluate the legitimacy of the view that current practices in tree breeding programs are potentially damaging to forests. Has this all been resolved to everyone's satisfaction in the past? John Muir : Naturalist. Speaking of the environment, "When we try to pick out anything by itself we find that it is bound fast by a thousand invisible cords that cannot be broken, to everything in the universe." Scientists at the University of Neuchâtel, in Switzerland (Matthias Held & Sergio Rasmann) discovered that the ability to secrete the natural substance E-beta-caryophyllene from corn roots was accidentally bred out during selective breeding to increase …

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  22. Title: Cytogeneticist Hi Everyone! I'm Tom, and I have a cytogen opportunity I wanted to make you aware of. Thanks! Location: Arizona Job Type: Fulltime / Permanent Environment: Commercial, high volume medical genetics testing & research laboratory Excellent salary and relocation assistance offered. This is an industry leader! Keywords: cytogenetics, medical genetics, diagnostics, molecular genetics, clinical cytogenetics, oncology, cancer genetics Reply to: patrickintl@sbcglobal.net Patrick International, Recruiters specializing in Molecular Medicine Positio…

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  23. Started by Smbat Gevorgyan,

    Hello everybody, my name is Smbat, I am from Armenia, I am a master's student. Genetics is my future profession and now I am doing my thesis work. But I have difficulties to find proper web site to use information from it. Could anyone be so kind to advise me web sites which would contain a lot of up to date information about everything which concerned with genetics.

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  24. Started by readytogo,

    Hi, I have a bunch of genotype data (14 mutations and 312 samples). I have inferred the haplotypes (total of fifteen different haplotypes) and identified that there is LD between three pairs of SNPs. I have done all this using Arlequin and Phase software. What I need to do is identify if any of these haplotypes are the result of recombination. I understand that LD is eroded by recombination but I am just confused by the whole concept. I even get confused with the four gamete test! Can anyone help me with this? I can give more info if needed - i think I have just totally confused myself and I cant find any software that identifies the haplotypes produced by rec…

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  25. Started by puzzly,

    Hi all, My husband and I both have short eyelashes, but our daughter has lovely long eyelashes. I didn't think this was possible. Can you explain? Thanks, Leanne

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