Genetics

A number of animals such as ants, jellyfish, sponges, slime mold slugs and even we humans are multicellular colonies or live as social groups. Is that explained through genetic evolution? How?

Do all DNA have same length Telomers or it depends on the chromosome type ?

Hello My friend and I are cross breeding a female geoffrey's cat to a male f4 bengal (domestic cat at this point). The problem is that geoffrey's cat has a different number of chromosomes than the domestic bengal. The geoffrey's has 36 while the domestic has 38. This should give the resulting hybrid 37 right? Now this cross has been done the other way numerous times to make what is called the safari cat. In this cross a male geoffrey's is mated to a female domestic. It produces very large kittens and resemble the wild parent geoffrey's cat alot. The geoffrey's cat is completely missing f series of chromosomes (which are some of the more pronounced chromosomes in the dome…

In the review section of my textbook (not for marks, don't worry. In my class marks come only from the midterm and final exam) there's a question which I'm not entirely sure how to calculate; namely because it sounds like a trick question. The first part was fairly easy: If someone with the genotype aa mates with someone with a genotype that's 0.5 Aa/0.5 AA, what is the probability that their first child will be affected (i.e. have the genotype aa). (This question is about a rare autosomal recessive allele). This is the calculation (I think): P(aa) = 0.5Aa x 1.0aa x 0.5(aa) = 0.25 aa. But the next part is what has me a little bit confused, because it asks what th…

I am a student of the arts and am currently putting together a thesis for my final paper, which may be around 8 pages. Our subject has to relate to Darwin. After reading On the Origin of Species I found that it was Darwin who first scientifically observed albinism. In his journal, he suggested that melanin may affect development, not only pigment. He also made the connection between albino cats and deafness. Local libraries and online and college databases seen to offer me NOTHING. Here is what I need: Any and all information on Darwin connecting to albinism. Offer sources. Thank you all so much! I really need the help, and soon.

i have a project on oryza sativa (rice) and i need the following information. plz help 1. what is microsatellite mapping? 2. how is it done? 3. has microsattelite mapping been done for oryza sativa indica group? plz also let me knw any references (scientific papers) regarding the above information.

I'm thinking about doing the National Geographic DNA test that traces your ancestry, and I was wondering if there are any good reasons to choose between the male and female line when you decide which path you want them to track. Is one more accurate than the other? What are the differences between the two? Thanks. Edit: Here's the description from the NG website:

What is the length of an uncoiled human DNA?

I need the genomic sequence for indica basmati (aromatic) rice.... i have searched all online rice databases as well as NCBI database but did not find anything. The sequence for oryza sativa indica is available but i need the sequence for basmati rice in particular. please help. i only need the sequence for chromosome 8. where can i find it? is it available on any online database? .... or can i get some information about any ongoing project working on this sequence?? help plz!

Does anyone know whether there's any reason why a karyotype either couldn't be done at all on, or else would not be practical to perform on, nerve cells? If I'm not mistaken any cell with a nucleus should be able to at least in theory be karyotyped. I strongly suspect that this review question has a typo in it somewhere.

What I mean is when for example a black person mixes with a white person and the baby comes out light skinned. Then that baby grows up (preferably female) and then mixes with a white or an east Indian or an Asian man. I'm asking this because I want to write a paper in a college English class on this subject. Also where can I communicate with people that have done this ? So I can see an example of it.

I am trying to see if the GFP protein is used with anti-bodies to label the proteins OR something else. It says GFP can be fused to any protein of interest using standard methods of recombinant DNA. I guess that means that an antibody isn't necessary but...what in the ^&$! is a standard method of recombinant DNA? HELP!

Hi everyone! Considering that many GWAS studies have failed to find susceptibility genes with high penetrance, therefore not explaining most of the heritability of many diseases, which approach could be more sensitive for capturing signals of susceptibility variants to complex diseases, in your opinion: sequence exome of many unrelated affected individuals and compare to controls or sequence affected and normal individuals from familial cases and combine the results with linkage analysis... Thanks!

Does the solenoid refer to the nucleosome before supercoiling?

What primers would we use to make cDNA of 16S rRNA?

people please let me know how can we distinguish between 2 identical DNA fragments(in terms of both size and sequence),one isolated from bacteria and other generated by PCR,by restriction enzyme digestion............give me link if possible along with your answer

people can anyone tell me why are we getting smear rather than bands after gel electrophoresis in southern blot technique?

Hello there, I have been an avid breeder of working border collies for about 15 years. I have a friend that has been breeding for about 5-8 years now and has come up with a question that I cannot answer. He has a Black/White border collie male that he breeds to another Black/White female and gets a female pup that is Black/White. He then breeds that female back to her Sire. Both Black/White, but he always gets a Red/White pup in the litter. He kept a Red/White male out of that litter and bred it back to a 1/2 sister that was Black/White and has in the past litters produced at least 1 r/w pup, but when crossed on the Red/White sire, did not produce any r/w …

Is the fetus a human? Or is it something else other than a human? Because it would seem that a fetus would satisfy the criteria of being human; it is part of the human species and shares our genetic makeup. But then I have this nagging in my brain that tells that a single cell also has the same genetic makeup, but is not considered a human. Anyone wanna clear my confusion up?

Alright so if I am understanding it right for a person to have Amber/Gold eyes you have to have a mutation. What I can't seem to figure out is a mutation of what. Is it more common in certain nationalities? What is this eye color dominant and recessive over, Though I would assume it is recessive over everything. Can it be passed on to children? Everything I have read on this topic has been very basic and I would like to know more of the specifics.

Dear forum, I wish to perform some haplotype analysis around a specific gene located on chromosome 5. I wish to know how I obtain the known genetic markers (SNPs, STR's etc) around this region which I can use to perform this analysis. Does anyone know of such databases? I have tried dbSNP, however their search function does not appear to be working, many thanks in advance, Jonathan

So I am doing some work on statistical analysis of DNA microarray data, and one thing I notice is that the sample size is often quite small. For example, in Alon etc all they only have 62 tissue samples. I was just wondering why there is often a low sample size?

recombinant DNA consist of a vector and the gene which is needed to be cloned ........after getting access to a cell the vector along with gene multiplies and after cell division we get multiple copies of the recombinant DNA.........can anyone tell me what happens to the vector part of recombinant DNA after the gene cloning process is complete.........as per i know it remains in the progeny......but our purpose is to clone the gene not the vector which is carrying it ........so finally the vector should be removed from the cell but this is not the case ..........why is it so?

As a control in an experiment, I stored a sample ofrestriction enzyme to be used (3µL of Hind III) in a 37ºC incubator for 5 days- and it still worked just as well in a Lambda digest as samples stored at-20ºC! I wanted to show how the enzyme was inactivated, or at least lessactive, after storage at 37ºC - but couldn't. Why do all digest protocols recommend keeping these enzymes on ice while using them - when 5 days atat 37C didn't have an effect. Any ideas? I performed the test twice, not a pipet error because another control (no HindIII) showed no digestion as expected. I realize heat inactivation is 65C, but expected less activity at least. Can't find an answer on t…

Hello, I work in the field of evolutionnary ecotoxicology and I have this SNP in my dataset that is quite weird : this marker is always homozygous. It is supposed to be a nuclear marker since it was picked on 454 sequence alignements of expressed RNA (from yellow perch). The sequence that surrounds this marker was blasted online and it does'nt correspond to any mitochondrial sequence available online. Furthermore, I tried to align this same sequence on a full lenght yellow perch mitochondrial DNA sequence and it does'nt align... Of course, this could be due to mis-priming. The primer designed to genotype this marker (Kaspar technology; KBiosciences) could be n…