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PhilGeis

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Everything posted by PhilGeis

  1. There are more things in heaven and Earth  Horatio than are dreamt of in your philosophy.

  2. Suggest you consider an application - relevant evaluation of efficacy in addition to MIC/MBC. There's no shortage of compounds reported in literature/patents to have "broad spectrum" efficacy at low concentrations.
  3. https://www.scmp.com/news/china/science/article/3117807/what-do-sinovac-coronavirus-vaccine-efficacy-results-mean This is just a news item - perhaps ask your employer for actual report
  4. Perhaps add aq. solubility as secondary dev objective
  5. The only interpretation is an observable zone of inhibition +/-., please don't attempt additional interpretation. Some use solvents like DMSO or ethanol in MIC testing of materials of limited aqueous solubility - generates numbers but introduces another variable. II'm with Charon on the testing. It's not hard find materials showing some degree of inhibition in such testing. Patent and tehnical literature is full of such gee whiz reports. What will you do with materials of some antimicrobial capacity?
  6. How developed is this effort and to what eventual application are you thinking? Potential use as chemotherapeutic agents would be decades away but there are near term commercial applications that might find this of value. There is so little research into the latter that even early efforts get attention.
  7. Disk diffusion (aka Kirby Bauer) does not give quantitiative results, and you should ot assume a "dead zone." You're looking at inhibition of growth. Your scenario of concentration dynamics after growth "has ceased" is not realistic - do not wate time on it. If you stuff is that isoluble you need another test protocol. Quantitative estimates can be obtained by microbial inhiibtion testing - typically determining growth in context of serially diluted the test compound in liquid (broth) growth medium inoclated with test micororganisms. Here's on group's description - https://emeryp
  8. Yes - they did not look ar cultural factors - an unaddressed variable that confounds. Dismissing this uncontrolled variable as "pockets" orthodox Jews doesis not justified. Jobs - then one would have to address unemployment as well - didn;t see that addressed here. Appealing to economics is not justified - coincidence is not cause and "larger patterns" is a cop out.
  9. Design is one element - another is performance in context. What is flow rate and how will it effectively filter enough room air (volume.time.flow) to really reduce risk.
  10. Think we discssued this on another forum. You, can use surfactant supplementation to inhibit colony size and can count at earlier time points, marking colony foci. Think you are workmin g with A. brasiliensis 16404 - that grows well enough at 3-4 days to coount.
  11. Her response it likely to be - we're all about "me". Folks get vaccinated for their own sake - not that of others.
  12. Thanks - I understand the potocoll. Likely's seem pretty subjective. "Much less likely" - on what basis is that assumption offered? Certainly cultural differences have been reported in willingness to obtain vaccination. If the nature of the job is a primary contributing factor - edvcuation rather than wealth per se would appear to be root cause.
  13. In terms of "unproven" - what specific social factor(s) associated with "inequality" was responsible for the observed difference? Could it be a cultural - in terms of difference in distancing and mask use practices?
  14. Sunscreens are drugs in US, and TiO2 in the products may "block" UV light and is also photoactivated to produce free radicals. France banned E171 (commercial TiO2 used in many products) in 2020 (https://www.europarl.europa.eu/doceo/document/E-9-2019-003009_EN.html) observing there was not enough data to confirm its safety in context. Subsequent research has challenged the study that provoked the ban https://scitechdaily.com/france-banned-this-common-food-additive-the-fda-says-is-safe-who-is-right/ and https://www.sciencedirect.com/science/article/pii/S0278691519305836?via%3Dihub
  15. What you should take away from these observations is that microbes are everywhere. They're not necessarily growing - may be present as dormant spores. As RobertMD observed - it does look like Rhizopus sp. (look for it on Google images) but it's neither possible to identify specifically the microbes from the pictures nor estimate the health of using the water bottle bsed on th pictures.
  16. Can you ;provide data for covid-related increases in antibiotic use significant to development of resistance?
  17. I'd not take a book as reliable cite for patient zero. What are the relevant published data?
  18. Sounds pretty subjective. Sure seems as a leap - a federal law requiring Ken's imagined and tbd "HSDS"? I doubt this will enjoy fed legislative priority.
  19. Does your HSDS and it's grading algorithm exist at this point?
  20. I don't think MSDS sheets are relevant. They largely and briefly report specific data with some very limited stuff on disposal and safety. You need more for a protocl.
  21. Don't think the public would comprehend such protocols. Relevant articles:, latter cites ASHRAE standards. https://www.achrnews.com/articles/105354-a-guide-to-best-practices-in-hospital-iaq and https://www.csemag.com/articles/indoor-air-quality-in-hospitals/
  22. Perhaps hospitals have established relevant protocols. HSDS is your term.
  23. https://www.mintie.com/assets/img/resources/ASHRAE_Article-on-VentilationChanges.pdf https://www.cdc.gov/mmwr/preview/mmwrhtml/rr5210a1.htm
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