I’m currently studying about collagen. And i have a couple of questions i can’t find in the litteraturen. I’m sorry for my Eng, it’s not my nativ language.

I understand that the H-Bonds betwine Alfa-strands in tropocollanin occurs with hydroxyproline, but to what Other  aminoacid  does it connect to? Is it betwine another hydroxyproline in the next strand
?

is the h-Bonds betwine tropocollagen aswell? Or is it only allysin- lysine covalent bonding?

what happens with the bonds when the cell gets Old? Does it increase or decrease? My guess is that the more interaction the more bonding occurs, thats why old ”meat” gets so chewy. ? Or?

Does this help?

 

You will find the hydrogen bond description near the end of the collagen article on the second attachment.

 

Revised second page

Awsome, it sais that glycine is a proton donor and the accepter is the CO group of hydroxyproline. 
 
 

what bok is that? ’it has alot of information that our book left out. 

 

Thank for the help. 

39 minutes ago, Niklas said:

Awsome, it sais that glycine is a proton donor and the accepter is the CO group of hydroxyproline. 
 
 

what bok is that? ’it has alot of information that our book left out. 

 

Thank for the help. 

Stryer

https://www.google.co.uk/search?source=hp&ei=-veQXYC_Goyua-TslrgG&q=stryer+biochemistry&oq=stryer+&gs_l=psy-ab.1.0.0j0i7i30l2j0l3j0i7i10i30j0i10j0l2.238.7244..10416...0.0..0.178.800.5j3......0....1..gws-wiz.......0i131.hPo-QpUYwIA

 

I'm suprised your text has less, Stryer is good but not specifically medical.

This one has a great deal more  detail about collagen.

https://www.amazon.com/Biochemistry-Concise-Text-Medical-Students/dp/0702014443

Edited September 29, 20196 yr by studiot

It has been a long time since I looked into this; however, I am under the impression that the hydroxyproline residues, the hydroxyl groups on the side-chains form hydrogen bonds to water.  For whatever reason the presence of hydroxyproline residues increases the thermal stability of collagen.