Genetics

I breed snakes and work mainly with color and pattern mutations for the pet trade. I’m having difficulty understanding the inheritance of a trait I’m working with. I’ll call that trait “B”. I’m working with a small sample size but I think the following are true: Normal male x B female gives B females and normal males VERY RARELY a B male B male x normal female gives B females never a B male B male x B female gives B females and B males, no normal types (this is based on one breeding) About 60 B animals have been produced, only 5 of these have been males (all produced for B x B breedings) A B male has never produce a B male when bred to a normal…

If a population is 50% black on their paternal side (Y-DNA) and 50% white on their maternal side (mtDNA), will the autosomal loci of that population reflect both of those ancestries equally (50/50), seeing as how autosomal loci are biparentally inherited? Or is it possible that because of autosomal recombination, both paternal and maternal genetic contributions will be skewed so that the combined autosomal loci of the population will reflect 20% black and 80% white ancestry? Please back up your answer with hard evidence gleaned from scientific papers. Another way of expressing my question is, does Y-DNA + mtDNA = x/2 = autosomal DNA, assuming that we inherit 50% …

I need help with my yeast 2 hybrid screen:( Can I get many false positive (blue) due to my own reagents? I am looking for interactions between several genes. I have started by checking whether my Yeast strain auto-activated. And surprisingly it does! I have bought and tested few strains and all auto-activate! I am now questioning my X-Gal, LacZ, and filter/nitrocellulos papers! Can I get soooo many false positive because of my reagents, or it is true that my yeast auto-activate on their own?

What if mitochondria begins to evolve and can't be used as a factory to produce ATP, if this mutation in the mitochondria spreads, will the human race die out?

hi.. bioluminescent in plants can be achieved through gene modification?

First off, this is my very first post. Forgive any errors. I am curious to know if genetic mutations can be predicted within a given population, given a certain amount of time. I can certainly understand that predicting exactly what mutation will occur could very well be nearly impossible. I am, however, interested in knowing if we can say that a mutation could probably happen within X number of years, within a population number of X. The population most likely will not remain a constant, but perhaps if we knew the size of a given population to begin with it might affect the prediction going out any number of years?

hey all!!!! i'm new here and am totally clueless about mitosis and meiosis...i'm beginner in genetics and so have no idea about the basic terms in this field:-(.... can someone plzz help me grasp this topic??? *asb*

I am by no means a geneticist...but I think genetic research into curing genetic diseases, prolonging lifespan, etc. are worthy research goals. With that said, I am wondering if anyone knows of research projects that the normal, average public can get involved with and help?

This question has been on my mind for years, and it's driving me nearly insane. Even if I get the answer, like, "Oh, it's just probability," I still would like a more in depth answer--how? For example, my family has some neighbors named Family A. In family A, the mother is alright-looking, while the father isn't that great looking, but he's a smart guy. The first son of theirs is fairly good-looking, but probably has Asperger's, got a perfect score on the SAT, etc. (He's the only on that actually looks like his parents).The first daughter looks like a downright model, with blonde hair and perfect skin. The second son just blows my mind. He is well over 6'4", Adonis-li…

How can we keep embryonic stem cells in an undifferentiated state??

Hello: I'm new in the forum. I hope someone could help me. I have a couple of samples of DNA aislated from a protozoan parasite 1 year ago. I did various PCR successfully. Now I have done some more PCR with the same DNA samples and same primers, all conditions are the same as in the past but, nothing work. I can't get good results. Someone has any idea what could be happening? My primers were diluted again for trying new PCR but nothig work. Help!!!!

I work with nematode (eukaryote) ribosomal DNA, In the literature I see that some times the 28S gene is refered to as the 26S gene or vice versa for different nematode species. Can anybody tell me whats the difference ?

Is it that perhaps certain lengths of DNA cause cohesins to be less tightened around the DNA, thus there is less chance for that strand of DNA to be kept in place? Is the Spo11 protein the only thing causing these breaks? Are the breaks soley dependent on the Spo11 protein?

Hello I'm getting slightly confused with a part of one of my projects, I'm trying to write about elevated cortisol levels that have been passed on epigenetically from fetal development, my understanding is that cortisol is released with adrenaline to give you a mental a physical fight or flight response, cortisol then stays in the body longer which if prolonged will ultimately wear out your heart and deteriorate the hippocampus. But I've read a couple of different articles that say different things, some say cortisol is released to slow down the production of adrenaline and if too much adrenaline is produced then more cortisol is produced, but because cortisol st…

So, let's say I have this: pUC18 vector: http://www.lgcstandards-atcc.org/attachments/1477.jpg What does it matter that the polylinker is in there? Isn't there the probability that the cut sites will already be present in other sections of the plasmid? Or this kind of vector such a standard that the enzyme restriction sites won't be found anywhere else but in the polylinker, thus creating a confined place to put the insertion?

I'm looking at the action of the Sau3A enzyme. What exactly is it cutting? 5'--- What does that third hyphen represent? Picture attached.

Imagine I'm making a pedigree In (I) [] = daddy (born 1978) () = mommy (born 1983) In (II) [] = son (first born child) () = daughter (second child) I..[]--() ......|... ......|... II.[]--() Or does it not matter which parent was born first? I..()--[] ......|... ......|... II.[]--()

First off hi I am a new user and posted this in biology but thought I should have posted it here in the genetics forum of biology the first time. Im a 21 year old single male and have never been in a relationship with a female. My whole life I have been rejected by females. Throughout my middle school years and highschool years I was obese so that probably has a alot to do with why I was unable to get a girlfriend. The tenth grade was the last time I ever tried to date a girl I was tired of being rejected and accepted that i was undesired by females so I lost interest in them and stopped talking to them. My senior year in highschool I lost all my excessive poundage and I …

I know that: bromophenol blue – used as a marker since most proteins and nucleic acid are colorless. glycerol - It is a preservative and a weighing agent. but what's the purpose of SDS and tris base in SDS agarose gel electrophoresis

In another post, I mentioned that I am not a scientist, let alone a geneticist.... But I had a thought today that made me wonder if this has been explored by others yet. Namely, I wonder what would happen if one took the genetic material of a virus out, and inserted one's own genetic code (taken from a childhood sample perhaps) into that virus...and then had the virus injected into your own body. Would the DNA sample from childhood fix and repair your aging DNA as the virus invaded your body's cells? Would this kind of be like cloning one's self only...not cloning? hmmmm....

Currently I'm working on a Biology assignment. But I'm stacked on how endocrines regulate human sex organs. Please help....

I was curious if anyone has an idea how much the body genetically mutates over an average lifespan. Putting aside any ethical/moral issues, if people had tissue/genetic samples taken when they were born and froze these for use later in life, would the body still recognize it as 'self' or has it mutated so much over the years that it would now reject this original genetic makeup as a foreign substance? Knowing one's genetic makeup at birth would seem to be an ideal reference point as things only get worse as you age (from a genetic point of view). Would having access to such data not open up possibilities for fighting cancer? I'm totally disregarding costs and logi…

Assume under asexual reproduction, an indivual with two alleles A and a at a locus begin to give birth to offsprings. At the next generation (F1), is there possibly an individual with genotype AA?

Hi all, I'm looking to buy a guide to genetics and genetic techniques. I am a new PhD student who feels a little bit out of depth when it comes to the genetic side of things - I don't know much about PCR, in situ hybridizations etc but am going to have to employ those techniques soon and feel a bit overwhelmed by it all because I'm rusty on the basics. Can anyone suggest something that's not geared at the casual reader, but still easy enough to follow? Much appreciated

Currently i have been searching through the internet for information on how food (organisms) can be Genetically modified. All the sites i visited seem to be complicated and is really hard to comprehend. Please help:confused: