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RNA Primers & Okazaki Fragments

ahyaa
in Biochemistry and Molecular Biology

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Hi, I have a simple semantics question.

I have been reading some literature that seems to consider RNA Primers as part of Okazaki fragments, but this should not be so because Okazaki Fragments by definition are just the DNA portions synthesized on the lagging strand. Any opinions/clarifications on this?

Hi, I have a simple semantics question.

 

I have been reading some literature that seems to consider RNA Primers as part of Okazaki fragments, but this should not be so because Okazaki Fragments by definition are just the DNA portions synthesized on the lagging strand. Any opinions/clarifications on this?

 

I think it may be in reference to the Okazaki fragments being synthesized from RNA primers during the replication process. These are replaced by DNA bases by (I think) polymerase enzymes later on.

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So I've asked a couple professors and they all say that RNA primers are not part of the "Okazaki fragment," they're separate things by definition. Apologies for the seemingly trivial topic!

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