fairychild Posted November 19, 2004 Share Posted November 19, 2004 hi all gurus, does anyone know the therapeutic index of plutonium? thanks Link to comment Share on other sites More sharing options...
fairychild Posted November 19, 2004 Author Share Posted November 19, 2004 hi all gurus, does anyone know the therapeutic index of plutonium? thanks Link to comment Share on other sites More sharing options...
[Tycho?] Posted November 19, 2004 Share Posted November 19, 2004 Uh, I dont even know what a theraputic index is. So no. Link to comment Share on other sites More sharing options...
[Tycho?] Posted November 19, 2004 Share Posted November 19, 2004 Uh, I dont even know what a theraputic index is. So no. Link to comment Share on other sites More sharing options...
Jordan14 Posted November 20, 2004 Share Posted November 20, 2004 ratio of amount needed to produce leathal effects: to amount needed to produce theraputic results Link to comment Share on other sites More sharing options...
Jordan14 Posted November 20, 2004 Share Posted November 20, 2004 ratio of amount needed to produce leathal effects: to amount needed to produce theraputic results Link to comment Share on other sites More sharing options...
CPL.Luke Posted November 20, 2004 Share Posted November 20, 2004 do you mean in the realm of killinga tumor using radiation therapy? if so I would ask this in the medicine section other than that radiation won't produce therapeutic results and this thread should be in the pseudoscience section Link to comment Share on other sites More sharing options...
CPL.Luke Posted November 20, 2004 Share Posted November 20, 2004 do you mean in the realm of killinga tumor using radiation therapy? if so I would ask this in the medicine section other than that radiation won't produce therapeutic results and this thread should be in the pseudoscience section Link to comment Share on other sites More sharing options...
[Tycho?] Posted November 21, 2004 Share Posted November 21, 2004 A google search for theraputic index of plutonium yields you asking this exact questuon on discovery channel forums. Otherwise I can find no mention of such a thing for plutonium. Link to comment Share on other sites More sharing options...
[Tycho?] Posted November 21, 2004 Share Posted November 21, 2004 A google search for theraputic index of plutonium yields you asking this exact questuon on discovery channel forums. Otherwise I can find no mention of such a thing for plutonium. Link to comment Share on other sites More sharing options...
CPL.Luke Posted November 21, 2004 Share Posted November 21, 2004 yeah plutonium is toxic when injested no matter how little you intake for radiation therapy you don't use things like plutonium. the only radioisotope allowed for injesting is carbon-14 you will never find what you are looking for, and if the question would later result in an experiment you may want to read this http://www.nrc.gov/materials/miau/med-use.html Link to comment Share on other sites More sharing options...
CPL.Luke Posted November 21, 2004 Share Posted November 21, 2004 yeah plutonium is toxic when injested no matter how little you intake for radiation therapy you don't use things like plutonium. the only radioisotope allowed for injesting is carbon-14 you will never find what you are looking for, and if the question would later result in an experiment you may want to read this http://www.nrc.gov/materials/miau/med-use.html Link to comment Share on other sites More sharing options...
Gilded Posted November 21, 2004 Share Posted November 21, 2004 "the only radioisotope allowed for injesting is carbon-14" Yeah right! You know, with carbon-14 being in every living creature on Earth, you just might want to think it over before having even an extra dose. O-15, C-11, Tc-99m, hundreds of different isotopes of whatever... the list goes on. In PET (positron emission tomography, if someone wasn't familiar with the word) these are widely used. Edit: And if you meant that C-14 is an isotope used in tumor treatment or other forms of radiation therapy: not likely. Link to comment Share on other sites More sharing options...
CPL.Luke Posted November 21, 2004 Share Posted November 21, 2004 "With the exception of the use of 1 microcurie carbon-14 urea radioactive drug capsules for in vivo diagnostic use in humans, all internal or external administrations of byproduct material or the radiation therefrom to human patients or human research subjects must be done in accordance with a medical use license (or authorization) issued pursuant to NRC’s regulations in 10 CFR Part 35, "Medical Use." NRC licenses the use of byproduct materials in diagnostic devices in the practices of dentistry and podiatry as part of medical use. The medical use of plutonium in nuclear powered pacemakers is licensed pursuant to 10 CFR Part 70." so I took that to mean only carbon-14 is allowed for injestion radiation therapy is normally carried out using xray machines correct? also plutonium is man made, the odds of you having any in your system are low (except because of botched space launches and such) I don't think anybody would have come up with a therapeutic index for it because I don't think anyone would have tried using it therapeuticly, or would have only found it harmful. Link to comment Share on other sites More sharing options...
budullewraagh Posted November 21, 2004 Share Posted November 21, 2004 there are many more, including cobalt-60 and iodine-131 Link to comment Share on other sites More sharing options...
fairychild Posted November 22, 2004 Author Share Posted November 22, 2004 yea i wasnt sure whether this being medical or physic.. but anyway, i was interested particularly in the ED50 of plutonium, as i have read it's the most toxic substance known to men - so there must be a dosage that is not lethal but effective in terms of any possible therapeutical treatment. how much of Pu is lethal? Link to comment Share on other sites More sharing options...
YT2095 Posted November 22, 2004 Share Posted November 22, 2004 according to my book 0.5 nano grams is considered the toxic level, however it`s not clear whether that`s as a Poison, or the Radioactive aspect? I suspect it`s the Toxicicity as it also states Cumulative Poison. Link to comment Share on other sites More sharing options...
Gilded Posted November 22, 2004 Share Posted November 22, 2004 "also plutonium is man made, the odds of you having any in your system are low (except because of botched space launches and such)" You know, if you had a kilo of potatoes, I'd guess about 10 plutonium and/or americium nuclei disintegrate in there every second. That is a ridiculously low amount, but I like nitpicking. :> Edit: Plutonium has been found in tobacco too! In ridiculously minute traces though, once again. Link to comment Share on other sites More sharing options...
CPL.Luke Posted November 22, 2004 Share Posted November 22, 2004 I had heard ounce that we all have trace amounts in our system because nasa boched a launch that was carrying a nuclear reactor with a few hundred grams of plutonium in it that got spread all over the earth. and that you can detect this trace in every person on the planet Link to comment Share on other sites More sharing options...
swansont Posted November 23, 2004 Share Posted November 23, 2004 so I took that to mean only carbon-14 is allowed for injestion C-14 is probably not widely used for therapy because the half-life is so long (5730 years IIRC). You want something that will decay fairly rapidly. I recall injesting Barium for a test. Don't know which isotope. Link to comment Share on other sites More sharing options...
Gilded Posted November 23, 2004 Share Posted November 23, 2004 "I recall injesting Barium for a test. Don't know which isotope." Possibly 122 or 123. But don't they usually use isotopes that go through IT or B+, instead of EC? Link to comment Share on other sites More sharing options...
CPL.Luke Posted November 23, 2004 Share Posted November 23, 2004 "With the exception of the use of 1 microcurie carbon-14 urea radioactive drug capsules for in vivo diagnostic use in humans," so its for some kind of test not a radiation therapy Link to comment Share on other sites More sharing options...
Gilded Posted November 23, 2004 Share Posted November 23, 2004 I don't think there's any sense using C-14 even in tests, as it's plenty in every living organism already (carbon dating you know). Link to comment Share on other sites More sharing options...
CPL.Luke Posted November 23, 2004 Share Posted November 23, 2004 well it sounded like it is a substantial excess that you could detect, 1 microcurie Link to comment Share on other sites More sharing options...
budullewraagh Posted November 23, 2004 Share Posted November 23, 2004 as i have read it's the most toxic substance known to men i heard that botulinum toxin a was... Link to comment Share on other sites More sharing options...
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