How much is known about the developmental proteins of varying species?

[Genecks]

Given said genome of a mammalian species, such as a white tiger, how much is known about the proteins that are involved in its biological development? The proteins used to guide cell differentiation and control the genome in those different cells at different stages?

 

Can it be assumed that all the proteins necessary to sustain and allow cell differentiation exist in the egg and sperm for such a mammal?

 

If so, have scientists taken effort to document such proteins?

Is there a database or databases that discuss proteins that are used for developmental processes per particular species?

 

[CharonY]

Developmental proteomics is still ongoing even for model organisms like Drosophila and Caenorhabditis. It is still some way off before one can try a comparative analysis of different species. Unless, of course, you are talking about individual, characterized and conserved elements of fetal development, for instance. In the sequence databases you can hunt those down individually and e.g.align them, if you want.

Edited March 29, 2010 by CharonY

[Darwinsbulldog]

Given said genome of a mammalian species, such as a white tiger, how much is known about the proteins that are involved in its biological development? The proteins used to guide cell differentiation and control the genome in those different cells at different stages?

 

Can it be assumed that all the proteins necessary to sustain and allow cell differentiation exist in the egg and sperm for such a mammal?

 

If so, have scientists taken effort to document such proteins?

Is there a database or databases that discuss proteins that are used for developmental processes per particular species?

 

 

Carroll, S. B. (2005). Endless Forms Most Beautiful:The New Science Of Evo-Devo and the Making Of The Animal Kingdom. London, Phoenix.

This popular book by Carroll has some references on the topic.

He has also published [with others:-

 

Carroll, S. B. (2005). "FROM DNA TO DIVERSITY: Molecular Genetics and The Evolution Of Animal Design". Oxford, Blackwell.

[Genecks]

Carroll, S. B. (2005). Endless Forms Most Beautiful:The New Science Of Evo-Devo and the Making Of The Animal Kingdom. London, Phoenix.

This popular book by Carroll has some references on the topic.

He has also published [with others:-

 

Carroll, S. B. (2005). "FROM DNA TO DIVERSITY: Molecular Genetics and The Evolution Of Animal Design". Oxford, Blackwell.

 

Thank you. I'll look into those sources when I have more time.

 

This thread was created with a slight leaning toward the idea of re-creating the white tiger in case it were to go extinct. If we had complete documentation of the proteins involved in development of a certain species, such as the white tiger, how possible would it be to simply synthesize/recreate the cellular materials and then induce that formulated cell to undergo development, thus developing a newborn white tiger?

 

I suspect it would need a mother, but I'm thinking a regular tiger mother might work (despite white tigers being somewhat larger than other tigers).

Edited September 1, 2010 by Genecks