5-HT Posted February 9, 2009 Share Posted February 9, 2009 For eight months, I've been researching/collecting information on amphetamine. I'm able to describe "to a tee" how amphetamine's mechanism of action affect the brain upon consumption, and nearly everything else thereafter, but one detail I CANNOT find is amphetamine's "path" upon leaving the brain. Any help, please? Link to comment Share on other sites More sharing options...
iNow Posted February 9, 2009 Share Posted February 9, 2009 I don't personally know enough to say for sure, but does it actually have a "path" to "leave the brain?" Isn't it metabolized, broken into smaller pieces, then expelled? What have you learned in your research? What is the missing bit? Link to comment Share on other sites More sharing options...
DrDNA Posted February 9, 2009 Share Posted February 9, 2009 (edited) I typed 'amphetamine metabolism' in Google and this the second thing that popped up...... URINE EXCRETION RATE: Amphetamine is largely unaffected during metabolism. The entire dose is probably eliminated in the urine over a period of several days. About 30% is excreted unchanged in 24 hours in normal urine. In acidic urine, the amount excreted increases up to 74% and decreases to 1% in basic urine. METABOLITES: Phenylacetone, benzoic acid, and hippuric acid less than 25%; 4-hydroxyamphetamine, 4-hydroxynorephedrine, and norephedrine less than 10%. http://www.sdrl.com/druglist/amphetamine.html Edited February 10, 2009 by DrDNA Link to comment Share on other sites More sharing options...
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