Kandriera Posted March 27, 2023 Share Posted March 27, 2023 (edited) Hello! Is it possible to decarboxylate saturated carboxylic acids at a high temperature (above 400-500+)? I found an information that only beta-keto acids can be decarboxylated and some specific reactions using catalyst, but everywhere temperature is around 150-200C. However, if acids have been annealed above 500C+, is decarboxylation with an intermediate in the form of carbcation possible? Not only acids, but also other carbonyls? Edited March 27, 2023 by Kandriera Link to comment Share on other sites More sharing options...
chenbeier Posted March 28, 2023 Share Posted March 28, 2023 I think at that temperature everything will be cracked. Link to comment Share on other sites More sharing options...
BabcockHall Posted April 26, 2023 Share Posted April 26, 2023 A catalyst such as thiamine pyrophosphate can decarboxylate alpha-keto acids. Link to comment Share on other sites More sharing options...
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