Sohan Lalwani

Oh, thanks.

Evolution and creation clash frequently, especially among religious and scientific circles, I’m confused on your point

Ecology memes

I didn’t see my error prior👍 Thanks @exchemist I didn’t notice my error prior, apologies

Yes and?

Hello everyone! It would be of my great happiness if everyone could sign this https://chng.it/WdtWN8PPHM It’s a petition to designate a NOAA critical habitat for rice whales, please we need all the help we can get. As of this posts creation it has roughly 501 signatures, we all want to aim for 1,000+ Image credit goes too: https://www.fisheries.noaa.gov/species/rices-whale

Wasn’t the Perseid meteor shower last night? It looks almost exactly like what you have in your photo

Great Gatsby?

Simple, follow site rules For the millionth time, that’s all you have to do

@MJ kihara you do owe @swansont an apology if you didn’t give one already

I believe it’s best both of you clarify or make terms with the DM’s

I recommend suing DeepL translate, it’s much more accurate Albeit it may have less language options

They were the same ones we have now, minus a few that have been eradicated that originally decimated many such as smallpox Let me repeat what multiple people have been saying, it’s the fact that they did not have proper sanitation methods, vaccinations, modern medicine etc

I went back and reviewed the earlier part of your post, and I think I have a better grasp of how you view the behavior of the SN NNP and its process of being created and decayed. The concept of SN NNP being infused or created and then decaying reminds me somewhat of virtual particles or quantum fluctuations, but it seems you are proposing something that operates at an even more fundamental level. It is fascinating to consider a kinetic resonance flux or a sub quantum dynamic as the underlying mechanism bridging scales from the smallest echoes to more familiar quantum phenomena. Your openness about the idea still being a work in progress is quite good 👍 Scientific progress often begins with speculation and evolving models. Could you share more about what you currently imagine the SN NNP to consist of? Do you see it as a discrete entity or more of a transient state or pattern? Also, I am curious about your reference to the SP vector. Is that related to established concepts like scalar potentials, or is it a new construct unique to your model? 🤝

Again, thank you everyone for these great answers! +1 There are some wonderful people here, some though are a little easy to aggravate Don’t worry my friend

I believe overall it is true that in many cases we need our genes to function correctly, and deleting a gene entirely can lead to unintended side effects, particularly when the gene in question plays multiple roles in different tissues. However, there are situations in autoimmune disease research where targeted knockouts or partial gene silencing can be beneficial, especially when focused on non-essential inflammatory mediators or tissue-specific immune pathways. For example, silencing certain cytokine genes that are overactive in diseases like rheumatoid arthritis or inflammatory bowel disease has shown promise in preclinical studies. Regarding your point about stem cells and delivery, it is accurate that modifying all hematopoietic stem cells can be challenging, especially with viral vectors. But this area is advancing quickly. Non-viral delivery systems such as electroporation of Cas9 protein and guide RNA complexes are now widely used and can achieve high editing efficiencies while reducing the risk of off-target effects. In some trials, such as those for sickle cell disease and beta thalassemia, edited stem cells have achieved therapeutic levels of correction. This shows that while full replacement of all stem cells is difficult, editing a sufficient proportion can still be clinically meaningful. Also I never said this before, but thank you 😀 You are very helpful when I am discussing medically related topics

In the context of autoimmune diseases, the immune system mistakenly attacks the body's own cells, causing chronic inflammation and damage. These diseases are often caused by a combination of genetic and environmental factors. Many genes are involved, including those that control how immune cells recognize the body’s own tissues or how inflammation is triggered and controlled. CRISPR-Cas9 could be used to treat autoimmune diseases by modifying or disabling genes that are causing the immune system to overreact. For example, researchers may use CRISPR to knock out a gene that produces a protein involved in triggering inflammation. By turning off this gene, the level of inflammation could be reduced, and the immune attack could be slowed or stopped. Whether scientists choose to change the gene or simply turn it off depends on the nature of the disease and the role of the gene. In some cases, the gene may be producing a harmful protein, and turning the gene off entirely might be the best approach. In other cases, the gene might be faulty and producing the wrong version of a protein, so editing it to correct the mutation would be more effective. In either case, CRISPR-Cas9 allows scientists to directly interact with the DNA of the cells to either silence the harmful gene or to repair it. Some researchers are also experimenting with CRISPR methods that do not involve cutting the DNA, but instead temporarily silence a gene by interfering with its expression. This could offer a safer, reversible way to modulate the immune system without permanently changing the DNA. Right now, CRISPR is not yet being widely used in humans to treat autoimmune diseases, but it has already been tested in humans for other conditions. For example, CRISPR has been used in clinical trials for sickle cell anemia, certain cancers, and inherited forms of blindness. Most autoimmune disease studies are still in the research phase, using cell cultures or animal models to identify target genes and test delivery methods. Because autoimmune diseases are complex and involve many genes and pathways, scientists need to be careful in selecting the right targets and ensuring that editing one gene does not create new problems elsewhere. However, the research is progressing, and the article you quoted summarizes how CRISPR might eventually be used in both animal and human models to selectively and safely adjust the immune response. Hope this helped 😁

Well, I got roughly 2 more downvotes and I am pretty sure of who

I’m aware, I have had great luck so far

Out of curiosity I must ask why was I mentioned here 🤔

Perhaps, but i will continue to work on improving my reputation Thank you! Thank you for all the helpful information everyone 😁

Sure!

lol

At -28 now, very very close to getting 0 From there I will work up

lol anytime!