GWAS of sexual orientation

[Der_Neugierige]

I knpw that 23andme has done a Gwas of sexual orientation and they couldn't find a genetic association for male or female homosexuality. I guess individual prenetal hormonal and epigenetic processes are the major reason why some people are gay. But I have still the opinion that there is indeed a unknown genetic reason why some people are gay.

 

Can we say when a gwas was unsucessfull in finding a genetic association for a phenotype there isn't a genetic background existing?

 

 

They also have done two linkage analysis for male homosexuality. If the major cause for homosexuality is prental hormonal/epigenetic and male homosexuality is very common in the population, so those two linkage analysis are unworthy?

[CharonY]

No, you cannot say that there is no genetic background. Rather it is likely that it is multi-factorial so that a simple GWAS won't be able to identify associated genes.