Hi all

I have a question concerning transcription

Problem goes like this: If RNA pol transcribes DNA from right to left, write newly sinthetised mRNA along with orientations.

This is DNA:

5'-ATATCCCTAATCCG-3'

3'-TATAGGGATTAGGC-5'

 

I understand that RNA pol can't go from left to right in direction 3'-5', thus we are talking about transcribing DNA which goes in 5-3 direction.

So this is what I got a mRNA, and final solution to this problem:

 

3'-UAU AGG GAU UAG GC 5'

Is this correct?

Unfortunately no. 5'-->3' is the coding strand, while 3'-->5' is the template strand. RNA pol binds to the template strand, and transcribes in the complementary 5'-->3' direction, so the resultant mRNA reads 5'-->3', the same as the coding strand (which is why the coding strand is so named). The mRNA should read the same as the coding strand, except U subbed for T.

I read this question differently from Xalatan. IMO if the polymerase moves right to left, it will treat the top strand as the template strand.

https://en.m.wikipedia.org/wiki/Coding_strand

 

https://www.google.com.tw/search?q=coding+strand&oq=coding+strand&aqs=chrome..69i57j0l3j69i60.4917j0j4&client=ms-android-htc-rev&sourceid=chrome-mobile&ie=UTF-8#imgrc=N_H8uoPZ_vi3aM%3A