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X-Inactivation & Trisomy XXY

blazinfury
in Genetics

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I read that X-inactivation doesn't tend to happen in males, but then when someone is XXY, they are a male because of the Y. However these individuals tend to live. So does that mean that x-inactivation happens in males or else these individuals would die?

Not in XY males. If you have an extra copy or copies, it is fine to silence one or more of them.

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