Ghaz Posted December 2, 2011 Share Posted December 2, 2011 can anyone tell me what will happen if a virus enters intact within a host cell without releasing its genome ? Link to comment Share on other sites More sharing options...
CharonY Posted December 2, 2011 Share Posted December 2, 2011 Depending on how the cell gets into the cell (e.g. whether via endocytosis) I would assume that common degradation pathways such as ERAD or endosomal degradation take care of the virus. Link to comment Share on other sites More sharing options...
Ghaz Posted January 24, 2012 Author Share Posted January 24, 2012 will the progeny virus form.I mean will their replication take place? Depending on how the cell gets into the cell (e.g. whether via endocytosis) I would assume that common degradation pathways such as ERAD or endosomal degradation take care of the virus. Link to comment Share on other sites More sharing options...
CharonY Posted January 27, 2012 Share Posted January 27, 2012 It won't be able to replicate if it cannot at some point expose its genetic material to its host. Some infection pathways actually require the intact virus to be internalized, but at some point the nucleic acid (be it RNA or DNA) will be delivered to the host and eventually translated. If the host does not produce the material required for virus assembly, there will be no propagation. Link to comment Share on other sites More sharing options...
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