genenerd Posted January 22, 2010 Share Posted January 22, 2010 the Constant Spring allele of the alpha-globin A2 gene produces a protein that is 172 aa's long rather than the normal 141. The first 4 amino acids match normal alpha-globin, but aa#142 in Hb-Constant Spring is glutamic acid. What is a possible hypothesis to explain the mutation that created Hb-Constant Spring? What is going on in the DNA in transcription and translation? Link to comment Share on other sites More sharing options...
CharonY Posted January 22, 2010 Share Posted January 22, 2010 Take a look at the genetic code. What mutations may cause a longer protein? Link to comment Share on other sites More sharing options...
dttom Posted January 23, 2010 Share Posted January 23, 2010 What will it be when you read the DNA code or RNA codon corresponding to aa#142 in wild form? Link to comment Share on other sites More sharing options...
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