Apoptosis Posted December 31, 2009 Share Posted December 31, 2009 I was wondering why a disease that causes mononucleosis is associated with polyclonal activation? Isn’t mononucleosis just a rise in the number of monocytes in the blood? B cells are the ones responsible for polyclonal activation, so why are they involved in this scenario? Link to comment Share on other sites More sharing options...
CharonY Posted January 2, 2010 Share Posted January 2, 2010 Mononucleosis is caused by the infection with the Epstein-Barr virus. In the later phases it infects B-Cells. The infected B-cells in turn activate immune responses against them. Link to comment Share on other sites More sharing options...
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