techkasamba Posted May 1, 2009 Share Posted May 1, 2009 I am a trainee in a company which is producing 2-chloro-4-amino sulfonamide. They start with meta chloro aniline & did chlorosulfonation with CSA (chlorosulfonic acid) followed by SOCl2 (Sulfonyl chloride) & then amination using ammonia. When I referred Vogel, I found that R-H + ClSO3H = R-HSO3 + HCl R-H + 2 ClSO3H = R-SO2Cl + HCl + H2SO4 Where R - is aromatic benzene ring. Since Company is already using 8 times of theoretical value why they are using sulfonyl chloride. The product is formed like this R1-SO2Cl + NH3 = R1-SO2NH2 +HCl Where R1 - is meta chloro aniline radical kind of structure. Can anyone help me. Can I use any other starting material for this product Link to comment Share on other sites More sharing options...
UC Posted May 1, 2009 Share Posted May 1, 2009 You already asked this on sciencemadness.org and had it answered. SOCl2 is thionyl chloride. Link to comment Share on other sites More sharing options...
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