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tRNA controversy

asaroj27
in Genetics

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Uricil is methylated thymine, and can make the same Watson-Crick base pairs, so I don't think translation would stop all together.

 

Psst, thymine is methylated uracil. The T-arm requires to be highly conserved as it is one of the anchor form to maintain the shape of the tRNA. The modification (in this case methylation) ensure a higher stability. Also, the thymine is not directly involved in the codon pairing, so it does not have a direct effect on the translation per se, but rather has structural functions.

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