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Enzyme inhibition

dArKchiLd
in Biochemistry and Molecular Biology

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Does anyone know if sodium p-hydroxymercuribenzoate is a competitive or non competitive inhibitor of leucine amino peptidase?

p-hydroxymercuribenzoate attacks unspecifically the thiol groups and is therefore a non-competitive inhibitor. This is also reflected by the fact that it is an inhibitor of a fairly large number of enzymes.

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