Jump to content

Carnitine shuttle - where does CoA go?


Recommended Posts

There seems to be a discrepancy in what happens to CoA in the first step of the carnitine transport:

1. Some sources show, that CoA gets released in cytoplasm, while acyl-carnitine is transported to the intermembrane space

2. In other sources, acyl-CoA gets transported as a whole, and free CoA is left in intermembrane space.

Does anyone know which version is correct?

I've been trying to find out more about this, and the second option seems more supported, but what I don't understand is if CoA is released in intermembrane space, what happens to it afterwards? Is there a transport that moves it back to cytosol?

Link to comment
Share on other sites

Create an account or sign in to comment

You need to be a member in order to leave a comment

Create an account

Sign up for a new account in our community. It's easy!

Register a new account

Sign in

Already have an account? Sign in here.

Sign In Now
×
×
  • Create New...

Important Information

We have placed cookies on your device to help make this website better. You can adjust your cookie settings, otherwise we'll assume you're okay to continue.