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What is the medical and Genetical reason why people with Genotype AC are advised to marry partners with no other Genotype other than AA?

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I just need a clear fact and clarification(s) about this.

During the crossing out process of AS and AC....the resulting crosses are AA AS AC CS.

My question mainly is how dangerous is the CS genotype and how can it be managed?

Edited by Yemi_Abdul-azeez
Ommited words in topic

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