Jump to content

Clinical trial challenges

charlotte17
in Chemistry

Featured Replies

Does anyone know of any challenges related to clinic trial of pharmacotherapies particular in phase 2 and 3?

 

I have bio - availability, plasma half-life, compliance and side effects. Not sure which would fit where though.

Compliance seems rather a challenge of phase 3 and 4 studies; to a lesser degree phase 2.

 

Bioavailability, plasma half-life would seem phase 2 to me, and side-effects actually phase 1 or 2: some side-effects may already be observed in a preclinical phase in laboratory animals.

 

Efficacy is typically phase 3, whereas efficiency (cost-effectiveness) applies to phase 4 studies ...

 

Of course, the degree to which you may or may not extrapolate your results is a huge problem in phase 2 and 3 studies.

Archived

This topic is now archived and is closed to further replies.

Go to topic listing

Important Information

We have placed cookies on your device to help make this website better. You can adjust your cookie settings, otherwise we'll assume you're okay to continue.

Configure browser push notifications
Chrome (Android)
  1. Tap the lock icon next to the address bar.
  2. Tap Permissions → Notifications.
  3. Adjust your preference.
Chrome (Desktop)
  1. Click the padlock icon in the address bar.
  2. Select Site settings.
  3. Find Notifications and adjust your preference.