Sarahisme Posted May 28, 2005 Share Posted May 28, 2005 hey i am writing up my prac on the preparation of aspirin, and just can't seem to find any information on what the "published" or "accepted" yield is. In my experimetn i got 86% (which i think is a little high). Cheers Sarah Link to comment Share on other sites More sharing options...
Sarahisme Posted May 28, 2005 Author Share Posted May 28, 2005 oh yeah, i meant to ask... where can i find this kind of information? (or this specific piece of information?) Link to comment Share on other sites More sharing options...
Sarahisme Posted May 28, 2005 Author Share Posted May 28, 2005 oh and likewise for paracetamol (if anyone knows where this kind of info. exists ) ? Link to comment Share on other sites More sharing options...
Sarahisme Posted May 29, 2005 Author Share Posted May 29, 2005 lol, anyone at all? Link to comment Share on other sites More sharing options...
BenSon Posted May 29, 2005 Share Posted May 29, 2005 I'm not familiar with the preparation of aspirin. If it dosn't involve equilibriums and similar, your best bet is just to calculate the theoretical possible yield and compare yours to it. ~Scott Link to comment Share on other sites More sharing options...
Sarahisme Posted May 29, 2005 Author Share Posted May 29, 2005 yeah i have done that, but i was thinking that there would be a value for the yield that is got when it is done in industry or something like that...? thanks for replying btw Link to comment Share on other sites More sharing options...
BenSon Posted May 29, 2005 Share Posted May 29, 2005 Maybe try emailing the companies, they could possibly help. I have no idea what the industry standard is. ~Scott Link to comment Share on other sites More sharing options...
Sarahisme Posted May 29, 2005 Author Share Posted May 29, 2005 ok ,will do, thanks BenSon Link to comment Share on other sites More sharing options...
Skye Posted May 29, 2005 Share Posted May 29, 2005 If you have access look up journals online, eg. journal of the american chemical society. Link to comment Share on other sites More sharing options...
budullewraagh Posted May 29, 2005 Share Posted May 29, 2005 out of curiosity, what precursor did you use, and what did you do to obtain your final product? Link to comment Share on other sites More sharing options...
Sarahisme Posted May 30, 2005 Author Share Posted May 30, 2005 precurser? Link to comment Share on other sites More sharing options...
budullewraagh Posted May 30, 2005 Share Posted May 30, 2005 what was the base chemical you started with in your synthesis? Link to comment Share on other sites More sharing options...
Sarahisme Posted May 30, 2005 Author Share Posted May 30, 2005 for aspirin it was salicylic acid and for paracetamol 4-aminophenol Link to comment Share on other sites More sharing options...
budullewraagh Posted May 30, 2005 Share Posted May 30, 2005 so basically you esterfied the salicylic acid with ethanoic acid and you formed the amide of para-aminophenol with ethanoic acid. what catalysts did you use? Link to comment Share on other sites More sharing options...
Sarahisme Posted May 31, 2005 Author Share Posted May 31, 2005 catalyst, ummm H2SO4 and acetic anhydride Link to comment Share on other sites More sharing options...
budullewraagh Posted May 31, 2005 Share Posted May 31, 2005 how conc was the H2SO4? Link to comment Share on other sites More sharing options...
Sarahisme Posted May 31, 2005 Author Share Posted May 31, 2005 dunno only used 6 drops of H2SO4 Link to comment Share on other sites More sharing options...
Sarahisme Posted May 31, 2005 Author Share Posted May 31, 2005 but i think it was fairly strong Link to comment Share on other sites More sharing options...
budullewraagh Posted May 31, 2005 Share Posted May 31, 2005 well, you should have observed high yields Link to comment Share on other sites More sharing options...
Sarahisme Posted June 1, 2005 Author Share Posted June 1, 2005 ok yeah ,well 85% and 60% is good i suppose, so thanks yep thanks everyone Link to comment Share on other sites More sharing options...
Crash Posted June 1, 2005 Share Posted June 1, 2005 Lol, we did this lab at teh start of this semester for my organic chem class (aspirin not paracetamol) Link to comment Share on other sites More sharing options...
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