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Genetic predisposition to THC tolerance

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It appears the role of the AKT1 genotype has been implicated in THC tolerance.

 

 

Interestingly, delta9-tetrahydrocannabinol (THC) may activate the AKT1 gene in vitro and in vivo. This pharmacological activation of the AKT1 gene by THC might explain why THC administration is neuroprotective in Alzheimer's disease.

Edited by tkadm30

It appears the role of the AKT1 genotype has been implicated in THC tolerance.

 

 

Interestingly, delta9-tetrahydrocannabinol (THC) may activate the AKT1 gene in vitro and in vivo. This pharmacological activation of the AKT1 gene by THC might explain why THC administration is neuroprotective in Alzheimer's disease.

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Edited by StringJunky

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If antipsychotics enhances AKT1 signaling, does it increases THC tolerance ?

  • 3 weeks later...

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