CharonY
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Depends a lot on the system that you want to use. In general, if you want a deletion by homologous recombination you can create a deletion construct simply by PCR.
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I generally do not recommend web sites in order to get a general understanding of biology. The reason is that due their very nature web sites often deal with individual topics and really more suited to inform on facts rather than concepts. Usually text books do a better job in that regard.