Protein structure is a complex thing...and also confusing!
I was going through literature about protein structure prediction.
If given a primary sequence of a protein, how can secondary structure be reliably predicted? I am aware of tendency of aa to be associated with different secondary structures, is there a specific algorithm used for calculation of secondary structure?
Is there any other way to model a protein structure based on primary sequence besides homology modelling?
Thanks in advance for input and also for reading this!