Tomas Hajkovsky Posted August 17, 2015 Share Posted August 17, 2015 Hello, is it possible for large molecules of proteins - hydrolases (10 - 50 kDa) to be absorbed (in their -fully functional form) through the wall of small intestine to blood? Enzymes got to the intestine because it was protected against digestion in stomach by medicament cover. If yeas, is it possible through the mechanisms of persorption by slubs, tight junctions or by random lymphocytes carrying enzymes? Thank you for your answers! Link to comment Share on other sites More sharing options...
CharonY Posted August 17, 2015 Share Posted August 17, 2015 It would be incredibly inefficient and almost impossible to control the dosage. Typically anything larger is provided intravenously. That is why insulin (~5.8 kDa) pills are not available, for example (but there seems to be some work on it). Link to comment Share on other sites More sharing options...
Tomas Hajkovsky Posted August 30, 2015 Author Share Posted August 30, 2015 Thank you! Link to comment Share on other sites More sharing options...
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