scilearner Posted February 9, 2011 Share Posted February 9, 2011 In blood clotting disorders, clotting time is increased, but when there is plalete disorder clotting time is not affected. What is the reason for that. Aren't platelets required for blood clotting. Also when a fibrous mesh is formed, do red blood cells and platelets get stuck in it. Is it why blood clots. Thanks Link to comment Share on other sites More sharing options...
Mrs Zeta Posted February 9, 2011 Share Posted February 9, 2011 Platelets are essential in blood clotting. They clump together in order to initiate the blood clotting steps, by reacting with fibrinogen. Vitamin K is also needed. The resulting fibrin/platelet mesh traps red blood cells and forms the clot. Agents that inhibit platelets from forming a clot (such as aspirin) are used to prevent abnormal clotting within a blood vessel that can lead to a stroke or heart attack. However, the coagulation cascade is much more complicated and finely tuned. For a rather good summary see wikipedia (coagulation) Link to comment Share on other sites More sharing options...
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