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My confusion with IgE antibodies and allergy?


scilearner

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Hello everyone,

 

There was a simple question given, where there was a bee sting on a guy and the question asked was what is the antibody involved. The answer is IgE. Now my question is when there is bee sting for the first time, why do we called it an allergic reaction. I mean for an allergy to occur don't we have to be exposed to the antigen second time, so IgE attached to Mast cells will release histamine 2nd time. Also why aren't other antibodies like IgA ect not involed in a bee sting. Thanks :)

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