scilearner Posted October 18, 2010 Share Posted October 18, 2010 Hello everyone, What I just read is for type 1 diabetes mellitus, it requires an environmental factor (eg virus) and genetic determinant that allows the B cells to be detected as non self. Now I'm not very familiar with autoimmune diseases. My question is why does a virus have to come and trigger the autoimmune destruction of B cells. If B cells are alreadly genetically non self, shouldn't the body start attacking them without a stimulus? Thank you Link to comment Share on other sites More sharing options...
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