blazinfury Posted April 7, 2009 Share Posted April 7, 2009 I need to synthesize, Phensuximide. The molecule is attached below. I need to begin with a benzaldehyde. Any advice? Thanks. Link to comment Share on other sites More sharing options...
Kaeroll Posted April 7, 2009 Share Posted April 7, 2009 Found a decent (at first glance... I emphasise the brevity of my search here) looking paper on the synthesis of derivatives of your compound. The reference is Miller et al, J Am Chem Soc 1951, 73 (12), pp5608-5610. If you're looking for a retrosynthetic analysis I can't help you - I'm rustier than I care to admit with some of this chemistry. Link to comment Share on other sites More sharing options...
UC Posted April 8, 2009 Share Posted April 8, 2009 (edited) Big hint: start with a wittig reaction to make styrene. SN2 will be important later on. Think cyanide. Edited April 8, 2009 by UC Link to comment Share on other sites More sharing options...
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