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michler's ketone


jothimp

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Hi

 

Can anyone tell me a good solvent that will dissolve Michler's ketone (also known by the name 4,4'-bis-(dimethy1amino)benzophenone).

 

Thanks

 

Properties

Michler's ketone occurs as white to green-colored leaflets. It is practically

insoluble in water, slightly soluble in ether, and soluble in alcohol,

pyrimidine, and benzene. Michler's ketone is combustible (HSDB 2001).

 

Carcinogenicity

Michler’s ketone (4,4′-(dimethylamino)benzophenone) is reasonably

anticipated to be a human carcinogen based on sufficient evidence of

carcinogenicity in experimental animals (NCI 1979). When administered

orally in the diet, Michler’s ketone induced increased incidences of

hepatocellular carcinomas in rats of both sexes and in female mice and

hemangiosarcomas (primarily subcutaneous) in male mice.

No adequate human studies of the relationship between exposure

to Michler’s ketone and human cancer have been reported.

 

http://ntp.niehs.nih.gov/ntp/roc/eleventh/profiles/s113mich.pdf

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