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Hypertolerance

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Hi! Excuse my English.

 

Are there deseases, which are known to be caused by hyperfunction of immunological tolerance?

 

It seems to me, that these deseases should have two attributes:

 

1) they should be immunodeficiencies

2) they should have antigen specificity

 

So, AIDS is not hypertolerance, because it has not specificity (immunity lack concern with ALL antigens)

 

If there are not such deseases, then may the cancer be one of the case?

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