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GTP:GDP ratio


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Hello all,

 

I'm a newbie so please forgive me if this question has already been asked...

 

I was wondering if anyone knows anything about the cellular ratio of GTP:GDP. I would ideally like to know the nuclear ratio but I don't mind whichever compartment; in fact, any NTP:NDP ratio would also help.

 

Many thanks in advance!

 

Uplah

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I checked my biochem notes and I have written down that in a healthy liver cell, the concentrations are:

 

[ATP] = 5mM

[ADP] = 1mM

[AMP] = 0.2mM

 

The prof. didn't give a source, so I'm not sure how accurate the numbers are, but I would expect the ratio to be somewhere around 5-10. The other NTP/NDP ratios should be similar because of nucleoside diphosphate kinase.

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