Chinmay1988

Thank you so much

I was wondering if it is possible to run purified viruses in SDS PAGE gels? I am thinking of an experiment using hepatitis A virus and wanted to know its size in kDA. I do know that its ORF codes for a polyprotein which is 250 kDA in size, however if I load the virus onto the gel, will I get a similar size? Cheers

I am a newbie here and I apologize if this topic has already been covered. I had a question regarding co receptors involved in viral infection. How can one determine if a coreceptors is involved? These coreceptors may not bind to the viral coat and so binding assays will not give a result. Tissue tropism of certain viruses may be due to such co receptors, especially in hepatitis viruses. Can anyone help me?