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Duda Jarek

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  1. Obviously many are coming, naturally selected especially for faster spread, now e.g. also from South Africa: https://www.cnbc.com/2021/01/06/south-africa-covid-strain-a-guide-to-what-you-need-to-know.html Again good interview:
  2. Tomorrow EU starts mass vaccination https://www.france24.com/en/europe/20201226-european-union-begins-coronavirus-vaccine-rollout-as-new-strain-spreads ... as the new strains like UK's are quickly spreading - what do we know about vaccine efficiency for them? It is great that there are lots of them - covering various mechanisms, hopefully allowing for effective war with mutations (https://www.nytimes.com/interactive/2020/science/coronavirus-vaccine-tracker.html 3 approved, 5 limited approved, 18 in phase III). Very nice explanation of Pfizer mRNA vaccine: https://berthub.eu/articles/posts/reverse-engineering-source-code-of-the-biontech-pfizer-vaccine/, especially: - it uses Psi (1-methyl-3’-pseudouridylyl) instead of U (uracil) - works the same, but with weaker immune response, - uses synonymous codons with increased numbers of C and Gs (e.g. CUU -> CUG both encode Leucine), which are converted more efficiently into proteins, - two amino acids are changed comparing to virus spike protein (K,V -> P) to handle the problem of difference between pre- and post-fusion spike protein - this exchange into Proline makes them fold into the proper shape without being mounted to a virus (known since 2017 thanks to work on SARS-CoV-1).
  3. UK starts mass vaccination: https://www.bbc.com/news/uk-55218679
  4. U.K. Approves Pfizer Coronavirus Vaccine, a First in the West https://www.nytimes.com/2020/12/02/world/europe/pfizer-coronavirus-vaccine-approved-uk.html
  5. 18th November Pfizer 95 percent https://www.theguardian.com/world/2020/nov/18/pfizer-covid-19-vaccine-95-effective-and-safe-further-tests-show Time for another bid for Sputnik and Moderna
  6. 9th November: Pfeizer "90 percent efficient" https://www.the-scientist.com/news-opinion/pfizers-covid-19-vaccine-90-percent-effective-initial-data-68138 11th November: "Sputnik V 92 percent" https://www.aljazeera.com/news/2020/11/11/russia-says-sputnik-v-covid-19-vaccine-is-92-percent-effective 16th November: "Moderna 94.5 percent" https://www.nytimes.com/2020/11/16/health/Covid-moderna-vaccine.html Who's next? ... in the meantime e.g. https://www.marketwatch.com/story/pfizers-ceo-sold-5-6-million-worth-of-shares-on-the-day-of-its-big-vaccine-news-so-what-11605280170
  7. Sure, we can ask it using potential energy, e.g.: charged particle near atom behaves accordingly to superposition of Coulomb potential of electron being in all points, or maybe accordingly to single Coulomb potential: averaged over wavefunction?
  8. Electron has associated electric field, so asking about electric field of atom/orbital, is it superposition of electric field of electron being in each point, or maybe mean? For example placing another atom nearby, should their electrons somehow synchronize (e.g. van der Waals force)? Don't it require superposition?
  9. In other words: is electric field of orbital a superposition over electron being in all places, or rather mean?
  10. While electron and proton being far apart are allowed to be imagined as nearly point particles, when they approach ~10^-10m (or much more for Rydberg atoms), electron is said "to become" this relatively huge wavefunction - orbital, describing probability distribution of finding electron (confirmed experimentally e.g. https://journals.aps.org/prb/abstract/10.1103/PhysRevB.80.165404 ). Can we specify in what e-p distance this qualitative change happens? How to think about this orbital from QM interpretations perspective - is it superposition of electron (indivisible charge) being in all these places? E.g. in Many Worlds Interpretation, should we imagine that electron has different position in each World? In such superposition each electron is staying or moving? If staying, where e.g. the orbital angular momentum comes from? If moving, why no synchrotron radiation?
  11. Another very similar molecule is NH3 ... found e.g. on Pluto - not suggesting biological source only geological: https://advances.sciencemag.org/content/5/5/eaav5731 Detection of ammonia on Pluto’s surface in a region of geologically recent tectonism
  12. Oxygen-free environments seem characteristic for geological processes (?), and PH3 is similar to CH4 released by our geology - if phosphorus dominates instead of carbon, couldn't phosphine by synthesized in oxygen-free geological environments? "Geologic emissions of methane to the atmosphere": https://pubmed.ncbi.nlm.nih.gov/12430657/ ps. SH2 can be produced by bacteria: https://en.wikipedia.org/wiki/Hydrogen_sulfide#Biosynthesis_in_the_body Phosphine also occurs in Earth atmosphere ... and Jupiter: https://en.wikipedia.org/wiki/Phosphine#Occurrence Can be generated by bacteria: https://www.researchgate.net/publication/12507095_Phosphine_generation_by_mixed-_and_monoseptic-cultures_of_anaerobic_bacteria
  13. Here is their recent Lancet paper: https://www.thelancet.com/journals/lancet/article/PIIS0140-6736(20)31866-3/fulltext https://www.reuters.com/article/us-health-coronavirus-russia-vaccine/russias-covid-19-vaccine-showed-antibody-response-in-initial-trials-idUSKBN25V1I2 Looks promising, but there are some suspicions: https://www.cnbc.com/2020/09/10/scientists-question-russian-vaccine-trial-data-on-unlikely-patterns.html Yesterday WHO vaccine report: https://www.who.int/publications/m/item/draft-landscape-of-covid-19-candidate-vaccines A worse news, probably the most promising (AstraZeneca) trial is on hold: https://www.nature.com/articles/d41586-020-02594-w
  14. It is also crucial that it is local random choice: based on possible single steps, having characteristic length like use of single step. MERW can be seen as scale-free limit of GRW_k: using uniform (/Boltzmann) distribution of length k paths from given position: GRW = GRW_1 MERW = lim_{k->infty} GRW_k
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