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Everything posted by qed
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sunspot, If you have a model for all these things then draw scheme. Show its advantages compared to other models. If you arte citing known or established things, place a reference. Since you dont know how neurons work and since you are not studying current views of neurobiology, i consider this all as your own rethorical orgasm. Have fun, but do not confuse students. Your reasoning is really bad. The terms you use are defined by your self and most of them are no scientific categories. I strongly suggest that a mod moves this thread to the speculations forum.
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This is wrong. This is wrong too. Before you start teaching other people how the brain works, you should learn the molecular basis of neuronal functions first. There is no current flow along the axon or the dendrites. There is only a current flow across the membrane. The surface charge alters at a given position for a very short time period when an action potential is passing by.
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Despite the nonsense they are claiming, "Central dogma" is, although not often used today, really an official term.
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New evidence linking natural selection to speciation
qed replied to bascule's topic in Evolution, Morphology and Exobiology
There was an article in the german version of scientific american a few years ago, where they showed that an oocytic parasite causes reproductive isolation among insects. Different strains of the bacteria alter the cytoplasmic compatibility of a population, leading to a division into compatible sub-populations. I cant remember the name of the bacterium, but it acts among a huge variety of insects and has been considered as an explanation for the enormous diversity and radiation among insects. http://www.rochester.edu/college/BIO/faculty/Werren.html -
Im not sure if i got you right but i think i have to contradict. Have a look at structure-function relationships in biology. At the molecular level structure and function are the same thing. Every process that occurs strongly depends on the constituants. No. The models science developed in order to describe these processes can be "replicated" or simulated in an idealized fashion. Nothing more. A computer programme is a closed system where everything what happens is predictable. You cannot idealize life on the basis of scientific models and than claim that this should be alife. Even if all components were known your programme would still be a descriptive simulation.
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Sorry if i got you wrong. Thats correct. Absolutely. I think we have a consent. I only wanted to point at the population level because a lot of people blind this out when they try to understand evolution and focus on single genes and mutations. I think we all agree that that is not sufficient in order to get the big picture.
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The cause for evolution lies on the genetic level, or changes on the genetic level. I think we all agree about that. Yes, group selection is not occuring, as you said, individuals are selected out. Sometimes this selection is mediated by a single gene, thereby deleting itself from the genepool. But that is irrelevant for the further adaption or evolution of the population. The relevant aspect is, what genetic information remains in the pool after selection and what is its frequency and diversity. The manifestation (does that word fit here?) of evolutionary changes can first be seen in the following generations, and here we are on the population level. The individuals that survived didnt change, their genes didnt change. Life has to reproduce in order to change, and this is indeed reflected in the population. I definitely disagree. Evolution doesnt happen for the benefit and detriment of anything, there are just mechanisms. There are no trends, purposes or final goals or something like that. Its the genotype of an individual that gives the fitness in a certain environment. But its the genepool of a population that reflects its adaptive capacity and is therefor the more important aspect. An individual cannot adapt either a single gene.
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Im in the field of molecular cell biology, with focus on cell adhesion and polarity proteins.
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This will not happen as long as the reproductive capacity of the rest of the population is similar to the individual with the new allele. The new sea gull may grow a little faster as the rest, but without selectional pressure on the whole the population, this new gene will not penetrate. This is especially true for large populations, where random genetic drift is low. The gene may persist in the genepool with low frequency unless the "genotype" of its carriers is not unfavorable in any way (that means if they dont die for any reason). The relative frequency of an allele is increased only by the decrease of other alleles by the death of individuals. Therefore only shrinking populations change their genepool. Believe it or not, evolution does never act on a particular gene. Only genotypes die or survive, and the evolution of a species takes place on the level of the population.
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Can the molar extinction coefficient for NADPH vary?
qed replied to maddensd's topic in Biochemistry and Molecular Biology
well , the extinction is, as far as i remember, not that temperature sensitive, the buffer composition has a greater effect on the coefficient. Is it possible that your absolute extinction values were too high and therefor out of the linear range of the photometer? For common facilities the linear range ends about absorbtion values of 1,5. -
if you have purified substrate protein/peptide, you can measure the activity via standard enzym kinetics. Other possibility is to use radioactiv P as a tracer and detect the phosphorylation of your substrate.
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George Bush using religion to make decisions regarding cloning GRrrrr
qed replied to Sashatheman's topic in Politics
do you think the scientific community would be able to manage this kind of human research properly? like cloning, gene manipulation and culturing of human embryos? Even without being influenced by nonscientific politics, science would fail due its form of organization. There is too much competition and this work would be too important for scientific reputation. If there wouldnt be a restricted access to "objects" only for a few scientists (as it is currently in germany with repect to stem cells), everybody in the biomedical field would have to work on it in order to get high impact publications. And if we would start working on developmental aspects, experiments would be extended to later stages and so on. In order to study human brain development, we need a brain that develops. One step requires and legitimizes the next one. Where is the border? I do not believe in the sense of responsibility among scientists in general. There would be fake and bad taste. embryonic stem cell research has not proven to be that powerfull. Our understanding of the cell is, especially development and differentiation, is really poor. There are no basic questions in biology that require human embryos in order to achieve a major breakthrough. I mean basical not medical. Economic interests and pressure drives medical research forward and with human embryos that would be the real bad taste, probably without significant progress when compared to todays standards. -
Does the "selfish gene"-point of view explain anything that is not covered by general evolution theory? i didnt read all the links that were presented in this thread, but the essence that i got from this "theory" seems unlogical to me. What is the advantage of the concept to assign a general "purpose" to a species, just like being a host for a molecule that wants to be reproduced? I really do not get it. For me it sounds like this: "selfish biomass":D biomass has the purpose to expand spatially, no matter how it is achieved. that is why birds evolved, to transport Biomass to the sky, and the brain to develop a rocket to bring biomass into space. there is no purpose of anything in evolution, just mechanisms. did i miss something important to understand the theory?
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I wouldnt say impossible, just unlikely. the assimilation of co2 is indeed were unlikely and very slow. that is the reason why RUBISCO is the most abundant protein in the world. Each plant needs tons of it to get enough co2. under uncatalized circumstances, this reaction wouldnt take place.
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Consciousness exceeding genetic potential
qed replied to sunspot's topic in Evolution, Morphology and Exobiology
What is the "genetic potential" in that sense? How do you determine the pontential of a person or of anything else? I dont know "genetic potential" as a biological term. But it seems to be used in a restrictive way to set a range for adaptation or a limit for plasticity. I would say if something changes more than expected, then the potential was undervalued, and not that the potential itself changed. -
Hi, im new to this forum and id like to join this interesting discussion. My impression is that a lot of people forget an important fact when they compare the brain to a computer. In a brain, hardware and software are the same thing. So learning and thinking is to remodel the architecture of the system in a certain extend. I hardly believe that a computer will be able to do this. Can they alter the program to adapt to situations or tasks or do they just add things to expand their capacity? Is this reduction satisfactory to you? In my opinion it doesnt explain anything. the hydrogen bond is important for specific interactions between molecules, but it doesnt produce information. 2 Proteins that bind to each other and induce conformational changes dont produce information. The biophysical interactions are only transducer of information. The biological function depends on the persistance of the information by following interactions and this only occurs when specific interactions take place in a specific temporal and spatial context. The hydrogen bond is not even sufficient to explain protein stability. I hope i didnt get you wrong. Sorry for strange english.